Excessive activation of microglia and subsequent release of proinflammatory cytokines play
a crucial role in neuroinflammation and neurodegeneration in Parkinson's disease (PD) …

Parkinson's disease (PD) is a neurodegenerative disease that is generally thought to be
caused by multiple factors, including environmental and genetic factors. Emerging evidence …

The typical tire manufacturing additive 6PPD, its metabolites 6PPDQ and 4-Hydroxy should
be monitored because of their ubiquitous presence in the environment and the high toxicity …

Recent studies have demonstrated that brain may be considered as the target for aluminium
(Al) toxicity, resulting in development of neurodegenerative and neurodevelopmental …

Aluminium and cadmium are biologically non-essential metals with a role in
neurodegenerative and neuromuscular diseases. As an attractive model for …

Aluminum (Al), a neurotoxic element, can induce Alzheimer's disease-like (AD-like) changes
by triggering neuronal death. Iron homeostasis disturbance has also been implicated in …

Many reports demonstrated that aluminum maltolate (Almal) has potential toxicity to human
and animal. Our study has demonstrated that Almal can induce oxidative damage and …

Evidence indicates that complex gene-environment interactions underlie the incidence and
progression of Parkinson's disease (PD). Neuroinflammation is a well-characterized feature …

Aluminum (Al) is a neurotoxicant and cause β-amyloid (Aβ) peptides aggregation and tau
hyperphosphorylation. Hyperforin (HF) is one of the major active constituents of the extracts …

Background Alzheimer's disease (AD) is one of the furthermost advanced
neurodegenerative disorders resulting in cognitive and behavioral impairment. Citicoline …