[HTML][HTML] The interferon-induced protein BST-2 restricts HIV-1 release and is downregulated from the cell surface by the viral Vpu protein
N Van Damme, D Goff, C Katsura, RL Jorgenson… - Cell host & …, 2008 - cell.com
The HIV-1 accessory protein Vpu counteracts a host factor that restricts virion release from
infected cells. Here we show that the interferon-induced cellular protein BST-2/HM1 …
infected cells. Here we show that the interferon-induced cellular protein BST-2/HM1 …
[HTML][HTML] High guanine and cytosine content increases mRNA levels in mammalian cells
G Kudla, L Lipinski, F Caffin, A Helwak, M Zylicz - PLoS biology, 2006 - journals.plos.org
Mammalian genes are highly heterogeneous with respect to their nucleotide composition,
but the functional consequences of this heterogeneity are not clear. In the previous studies …
but the functional consequences of this heterogeneity are not clear. In the previous studies …
[HTML][HTML] HIV-1 Vpu neutralizes the antiviral factor Tetherin/BST-2 by binding it and directing its beta-TrCP2-dependent degradation
B Mangeat, G Gers-Huber, M Lehmann… - PLoS …, 2009 - journals.plos.org
Host cells impose a broad range of obstacles to the replication of retroviruses. Tetherin (also
known as CD317, BST-2 or HM1. 24) impedes viral release by retaining newly budded HIV …
known as CD317, BST-2 or HM1. 24) impedes viral release by retaining newly budded HIV …
[HTML][HTML] Vpu antagonizes BST-2–mediated restriction of HIV-1 release via β-TrCP and endo-lysosomal trafficking
RS Mitchell, C Katsura, MA Skasko, K Fitzpatrick… - PLoS …, 2009 - journals.plos.org
The interferon-induced transmembrane protein BST-2/CD317 (tetherin) restricts the release
of diverse enveloped viruses from infected cells. The HIV-1 accessory protein Vpu …
of diverse enveloped viruses from infected cells. The HIV-1 accessory protein Vpu …
[HTML][HTML] Multiparameter RNA and codon optimization: a standardized tool to assess and enhance autologous mammalian gene expression
S Fath, AP Bauer, M Liss, A Spriestersbach… - PloS one, 2011 - journals.plos.org
Autologous expression of recombinant human proteins in human cells for biomedical
research and product development is often hampered by low expression yields limiting …
research and product development is often hampered by low expression yields limiting …
Purification and characterization of HIV–human protein complexes
To fully understand how pathogens infect their host and hijack key biological processes,
systematic mapping of intra-pathogenic and pathogen–host protein–protein interactions …
systematic mapping of intra-pathogenic and pathogen–host protein–protein interactions …
[HTML][HTML] Toxoplasma gondii exploits the host ESCRT machinery for parasite uptake of host cytosolic proteins
Y Rivera-Cuevas, J Mayoral, M Di Cristina… - PLoS …, 2021 - journals.plos.org
Toxoplasma gondii is a master manipulator capable of effectively siphoning the resources
from the host cell for its intracellular subsistence. However, the molecular underpinnings of …
from the host cell for its intracellular subsistence. However, the molecular underpinnings of …
[HTML][HTML] Multilayered mechanism of CD4 downregulation by HIV-1 Vpu involving distinct ER retention and ERAD targeting steps
A key function of the Vpu protein of HIV-1 is the targeting of newly-synthesized CD4 for
proteasomal degradation. This function has been proposed to occur by a mechanism that is …
proteasomal degradation. This function has been proposed to occur by a mechanism that is …
Identification of two distinct human immunodeficiency virus type 1 Vif determinants critical for interactions with human APOBEC3G and APOBEC3F
RA Russell, VK Pathak - Journal of virology, 2007 - Am Soc Microbiol
Human cytidine deaminases APOBEC3G (A3G) and APOBEC3F (A3F) inhibit replication of
Vif-deficient human immunodeficiency virus type 1 (HIV-1). HIV-1 Vif overcomes these host …
Vif-deficient human immunodeficiency virus type 1 (HIV-1). HIV-1 Vif overcomes these host …
[HTML][HTML] HIV-1 Vpu and HIV-2 Env counteract BST-2/tetherin by sequestration in a perinuclear compartment
H Hauser, LA Lopez, SJ Yang, JE Oldenburg… - Retrovirology, 2010 - Springer
Background In the absence of the Vpu protein, newly formed HIV-1 particles can remain
attached to the surface of human cells due to the action of an interferon-inducible cellular …
attached to the surface of human cells due to the action of an interferon-inducible cellular …