Narrative review: statin-related myopathy

TR Joy, RA Hegele - Annals of internal medicine, 2009 - acpjournals.org
Statin-related myopathy is a clinically important cause of statin intolerance and
discontinuation. The spectrum of statin-related myopathy ranges from common but clinically …

Statin-induced myopathy: a review and update

TT Abd, TA Jacobson - Expert opinion on drug safety, 2011 - Taylor & Francis
Introduction: Statin-induced myopathy is an important cause of statin intolerance and the
most common cause of statin discontinuation. Observational studies estimate that 10–15 …

An assessment by the statin muscle safety task force: 2014 update

RS Rosenson, SK Baker, TA Jacobson… - Journal of clinical …, 2014 - Elsevier
Abstract The National Lipid Association's Muscle Safety Expert Panel was charged with the
duty of examining the definitions for statin-associated muscle adverse events, development …

Rationale and design of the CLEAR-outcomes trial: evaluating the effect of bempedoic acid on cardiovascular events in patients with statin intolerance

SJ Nicholls, AM Lincoff, HE Bays, L Cho… - American heart …, 2021 - Elsevier
Background Although statins play a pivotal role in the prevention of atherosclerotic
cardiovascular disease, many patients fail to achieve recommended lipid levels due to statin …

Discontinuation of statins in routine care settings: a cohort study

H Zhang, J Plutzky, S Skentzos, F Morrison… - Annals of internal …, 2013 - acpjournals.org
Chinese translation Background: Systematic data on discontinuation of statins in routine
practice of medicine are limited. Objective: To investigate the reasons for statin …

Acid-suppressive medication use and the risk for hospital-acquired pneumonia

SJ Herzig, MD Howell, LH Ngo, ER Marcantonio - Jama, 2009 - jamanetwork.com
Context The use of acid-suppressive medication has been steadily increasing, particularly in
the inpatient setting, despite lack of an accepted indication in the majority of these patients …

Red yeast rice for dyslipidemia in statin-intolerant patients: a randomized trial

DJ Becker, RY Gordon, SC Halbert… - Annals of internal …, 2009 - acpjournals.org
Background: Red yeast rice is an herbal supplement that decreases low-density lipoprotein
(LDL) cholesterol level. Objective: To evaluate the effectiveness and tolerability of red yeast …

[PDF][PDF] Statin myopathy: a common dilemma not reflected in clinical trials

G Fernandez, ES Spatz, C Jablecki… - … Clinic journal of …, 2011 - cdn.mdedge.com
Although statins are remarkably effective, they are still underprescribed because of concerns
about muscle toxicity. We review the aspects of statin myopathy that are important to the …

Treatment strategies in patients with statin intolerance: the Cleveland Clinic experience

WM Mampuya, D Frid, M Rocco, J Huang… - American heart …, 2013 - Elsevier
Background Statin therapy is a proven effective treatment of hyperlipidemia. However, a
significant number of patients cannot tolerate statins. This study was conducted to review …

[HTML][HTML] Intolerance to statins: mechanisms and management

R Bitzur, H Cohen, Y Kamari, D Harats - Diabetes care, 2013 - ncbi.nlm.nih.gov
Statins are considered very effective in reducing cardiovascular morbidity and mortality in
high-risk patients. However, although adherence to statins improves morbidity and mortality …