Improved vaccine against PRRSV: current progress and future perspective

Y Nan, C Wu, G Gu, W Sun, YJ Zhang… - Frontiers in …, 2017 - frontiersin.org
Porcine reproductive and respiratory syndrome virus (PRRSV), one of the most
economically significant pathogens worldwide, has caused numerous outbreaks during the …

Immunological solutions for treatment and prevention of porcine reproductive and respiratory syndrome (PRRS)

MP Murtaugh, M Genzow - Vaccine, 2011 - Elsevier
Vaccination is the principal means used to control and treat porcine reproductive and
respiratory syndrome virus (PRRSV) infection. An array of PRRS vaccine products is …

Influence of N-linked glycosylation of porcine reproductive and respiratory syndrome virus GP5 on virus infectivity, antigenicity, and ability to induce neutralizing …

IH Ansari, B Kwon, FA Osorio, AK Pattnaik - Journal of virology, 2006 - Am Soc Microbiol
Porcine reproductive and respiratory syndrome virus (PRRSV) glycoprotein 5 (GP5) is the
most abundant envelope glycoprotein and a major inducer of neutralizing antibodies in vivo …

The role of porcine reproductive and respiratory syndrome (PRRS) virus structural and non-structural proteins in virus pathogenesis

N Music, CA Gagnon - Animal health research reviews, 2010 - cambridge.org
Porcine reproductive and respiratory syndrome (PRRS) is an economically devastating viral
disease affecting the swine industry worldwide. The etiological agent, PRRS virus (PRRSV) …

Inactivated and subunit vaccines against porcine reproductive and respiratory syndrome: current status and future direction

GJ Renukaradhya, XJ Meng, JG Calvert, M Roof… - Vaccine, 2015 - Elsevier
Within a few years of its emergence in the late 1980s, the PRRS virus had spread globally to
become the foremost infectious disease concern for the pork industry. Since 1994, modified …

[HTML][HTML] Porcine reproductive and respiratory syndrome virus induces apoptosis through a mitochondria-mediated pathway

SM Lee, SB Kleiboeker - Virology, 2007 - Elsevier
As with a number of other viruses, Porcine reproductive and respiratory syndrome virus
(PRRSV) has been shown to induce apoptosis, although the mechanism (s) involved remain …

Development and Use of a Multiplex Real-Time Quantitative Polymerase Chain Reaction Assay for Detection and Differentiation of Porcine Circovirus-2 Genotypes …

CA Gagnon, JRE Del Castillo, N Music… - Journal of …, 2008 - journals.sagepub.com
By the end of 2004, the Canadian swine population had experienced a severe increase in
the incidence of Porcine circovirus-associated disease (PCVAD), a problem that was …

[HTML][HTML] Identification of virulence determinants of porcine reproductive and respiratory syndrome virus through construction of chimeric clones

B Kwon, IH Ansari, AK Pattnaik, FA Osorio - Virology, 2008 - Elsevier
In order to determine virulence associated genes in porcine reproductive and respiratory
syndrome virus (PRRSV), a series of chimeric viruses were generated where specific …

Skin-Based Vaccination: A Systematic Mapping Review of the Types of Vaccines and Methods Used and Immunity and Protection Elicited in Pigs

I Có-Rives, AYA Chen, AC Moore - Vaccines, 2023 - mdpi.com
The advantages of skin-based vaccination include induction of strong immunity, dose-
sparing, and ease of administration. Several technologies for skin-based immunisation in …

DNA vaccines co-expressing GP5 and M proteins of porcine reproductive and respiratory syndrome virus (PRRSV) display enhanced immunogenicity

Y Jiang, S Xiao, L Fang, X Yu, Y Song, C Niu, H Chen - Vaccine, 2006 - Elsevier
The two major membrane-associated proteins of porcine reproductive and respiratory
syndrome virus (PRRSV), GP5 and M (encoded by ORF5 and ORF6 genes, respectively) …