Sirtuin 1 (Sirt1) is a NAD+-dependent deacetylase that exerts many of the pleiotropic effects
of oxidative metabolism. Due to local hypoxia and hypertonicity, the renal medulla is subject …

ABSTRACT TGF‐β signaling plays an important role in the pathogenesis and progression of
chronic kidney disease (CKD). Smad3, a transcription factor, is a critical fibrogenic mediator …

Abstract Background Quercus acuta Thunb.(Fagaceae) or Japanese evergreen oak is
cultivated as an ornamental plant in South Korea, China, Japan, and Taiwan and used in …

Context: Silymarin, a flavonolignan from Silybum marianum (L.) Gaertn.(Asteraceae), has
been reported to have antioxidant and anti-inflammatory properties. Therefore, it may be …

Adipose-derived mesenchymal stem cells (AdMSCs) have been reported to have
therapeutic benefit in skin. The aim of this study was to examine the effects of AdMSCs in UV …

Silymarin, an extract from Silybum marianum, has been shown to have antioxidant
properties. However, there is no scientific report on wound healing activity of the silymarin …

Background Episiotomy is the most commonn surgical procedure in midwifery which as any
other wounds can cause infection or delay in healing. The current study aimed to determine …

Topical delivery of potent antioxidants maintain the redox balance of the skin, which leads to
the down-regulation of matrix metalloproteinase (MMP) expression and prevents UV …

Porphyra‐334 is a kind of mycosporine‐like amino acid absorbing ultraviolet‐A. Here, we
characterized porphyra‐334 as a potential antiaging agent. An in vitro assay revealed that …

One of the most difficult and treatment-resistant complications of Crohn's disease is the
development of fibrotic intestinal strictures due to mesenchymal cell hyperplasia and …