Piperidine nucleus as a promising scaffold for alzheimer's disease: current landscape and future perspective
Heterocycles and their derivatives hold an important place in medicinal chemistry due to
their vast therapeutic and pharmacological significance and wider implications in drug …
their vast therapeutic and pharmacological significance and wider implications in drug …
[HTML][HTML] True or False? Alzheimer's disease is Type 3 Diabetes: Evidences from Bench to Bedside.
Y Peng, S Yao, Q Chen, H Jin, M Du, Y Xue… - Ageing research reviews, 2024 - Elsevier
Globally, Alzheimer's disease (AD) is the most widespread chronic neurodegenerative
disorder, leading to cognitive impairment, such as aphasia and agnosia, as well as mental …
disorder, leading to cognitive impairment, such as aphasia and agnosia, as well as mental …
[HTML][HTML] Recent Development of Novel Aminoethyl-Substituted Chalcones as Potential Drug Candidates for the Treatment of Alzheimer's Disease
No drug on the market, as a single entity, participates in different pathways involved in the
pathology of Alzheimer's disease. The current study is aimed at the exploration of …
pathology of Alzheimer's disease. The current study is aimed at the exploration of …
Calcium Channels as a Potential Therapeutic Target for Alzheimer's Disease
P Sharma, P Thapak, B Chandwani, H Kharkwal… - … Drug Targets for …, 2023 - Springer
Alzheimer's disease (AD) is the most common type of dementia that characterizes the
accumulation of amyloid-β plaques and neurofibrillary tangles in the brain. AD is the most …
accumulation of amyloid-β plaques and neurofibrillary tangles in the brain. AD is the most …
N‑acetylcysteine prevents hypothyroidism‑induced impairment of learning and memory in adolescent male rats via affecting oxidative status, inflammatory response …
A Basiri, S Izadi, S Kakhki, V Alikahni, S Askarian… - Acta Neurobiologiae …, 2024 - ane.pl
The present study was assumed that N‑acetylcysteine (AC) might improve cognitive function
in adolescent rats with hypothyroidism through various mechanisms. Sixty adolescent rats …
in adolescent rats with hypothyroidism through various mechanisms. Sixty adolescent rats …
The effect of N-acetylecysteine supplementation on endothelial function: a systematic review
M Mahmoudinezhad, Z Ghavami, P Jamilian… - Clinical Nutrition Open …, 2023 - Elsevier
Background N-acetylcysteine (NAC) as a potent anti-inflammatory and antioxidant
compound, has raised scientific interest to affect endothelial function. The present systematic …
compound, has raised scientific interest to affect endothelial function. The present systematic …
[HTML][HTML] Accelerated amyloid angiopathy and related vascular alterations in a mixed murine model of Alzheimer s disease and type two diabetes
M Vargas-Soria, JJ Ramos-Rodriguez… - Fluids and Barriers of …, 2022 - Springer
Background While aging is the main risk factor for Alzheimer´ s disease (AD), emerging
evidence suggests that metabolic alterations such as type 2 diabetes (T2D) are also major …
evidence suggests that metabolic alterations such as type 2 diabetes (T2D) are also major …
Flutamide alters markers of inflammation and oxidative stress in experimental model of autism
Autism spectrum disorder (ASD) is a neurodevelopmental disorder withcomplex etiology
and phenotypes. Many clinical and pre-clinical study have demonstrated the association of …
and phenotypes. Many clinical and pre-clinical study have demonstrated the association of …