Tens of millions of contrast-enhanced magnetic resonance imaging (MRI) exams are
performed annually around the world. The contrast agents, which improve diagnostic …

In an era of personalized medicine, the clinical community has become increasingly focused
on understanding diseases at the cellular and molecular levels. Magnetic resonance …

We introduce a redox-active iron complex, Fe-PyC3A, as a biochemically responsive MRI
contrast agent. Switching between Fe3+-PyC3A and Fe2+-PyC3A yields a full order of …

Cobalt is an essential metal that is found in very low abundance in the body and the
environment. Cobalt coordination complexes exhibit interesting redox and magnetic …

Given their potential in a better characterization and diagnosis of major pathologies like
cancer or chronic inflammation, redox-activated Magnetic Resonance Imaging (MRI) probes …

We report a pair of fluorinated, redox-active copper complexes for potential use as 19F MRI
contrast agents for detecting cellular hypoxia. Trifluorinated Cu (II) ATSM-F3 displays the …

The physicochemical properties of lanthanide (III) ions are directly linked to the structure of
the surrounding ligands. Rapid ligand exchange prohibits direct structure–property …

Elevated levels of reactive oxygen species and peroxidase expression are often associated
with inflammation and inflammatory diseases. We developed two novel Co (II) complexes …

Magnetic resonance imaging (MRI) using redox-active, EuII-containing complexes is one of
the most promising techniques for noninvasively imaging hypoxia in vivo. In this technique …

Biological probes constructed from lanthanides can provide a variety of readout signals,
such as the luminescence of Eu (III), Tb (III), Yb (III), Sm (III) and Dy (III), and the proton …