Targeting neuroinflammation in Alzheimer's disease: From mechanisms to clinical applications
ZZ Si, CJ Zou, X Mei, XF Li, H Luo, Y Shen… - Neural regeneration …, 2023 - journals.lww.com
Alzheimer's disease is characterized by sustained neuroinflammation leading to memory
loss and cognitive decline. The past decade has witnessed tremendous efforts in …
loss and cognitive decline. The past decade has witnessed tremendous efforts in …
[HTML][HTML] The multifaceted nature of IL-10: regulation, role in immunological homeostasis and its relevance to cancer, COVID-19 and post-COVID conditions
Interleukin-10 (IL-10) is a pleiotropic cytokine that has a fundamental role in modulating
inflammation and in maintaining cell homeostasis. It primarily acts as an anti-inflammatory …
inflammation and in maintaining cell homeostasis. It primarily acts as an anti-inflammatory …
Astrocytic α2-Na+/K+ ATPase inhibition suppresses astrocyte reactivity and reduces neurodegeneration in a tauopathy mouse model
CN Mann, SS Devi, CT Kersting, AV Bleem… - Science translational …, 2022 - science.org
Alzheimer's disease (AD) is the most dominant form of dementia characterized by the
deposition of extracellular amyloid plaques and intracellular neurofibrillary tau tangles …
deposition of extracellular amyloid plaques and intracellular neurofibrillary tau tangles …
The muscle-brain axis and neurodegenerative diseases: the key role of mitochondria in exercise-induced neuroprotection
Regular exercise is associated with pronounced health benefits. The molecular processes
involved in physiological adaptations to exercise are best understood in skeletal muscle …
involved in physiological adaptations to exercise are best understood in skeletal muscle …
Curcumin as prospective anti-aging natural compound: focus on brain
T Benameur, R Soleti, MA Panaro, ME La Torre… - Molecules, 2021 - mdpi.com
The nutrients and their potential benefits are a new field of study in modern medicine for
their positive impact on health. Curcumin, the yellow polyphenolic compound extracted from …
their positive impact on health. Curcumin, the yellow polyphenolic compound extracted from …
Therapeutic utility of mesenchymal stromal cell (MSC)-based approaches in chronic neurodegeneration: a glimpse into underlying mechanisms, current status, and …
M Rahbaran, AO Zekiy, M Bahramali… - Cellular & Molecular …, 2022 - Springer
Recently, mesenchymal stromal cell (MSC)-based therapy has become an appreciated
therapeutic approach in the context of neurodegenerative disease therapy. Accordingly, a …
therapeutic approach in the context of neurodegenerative disease therapy. Accordingly, a …
Anti-inflammatory effects of four psilocybin-containing magic mushroom water extracts in vitro on 15-lipoxygenase activity and on lipopolysaccharide-induced …
SM Nkadimeng, CML Steinmann… - Journal of Inflammation …, 2021 - Taylor & Francis
Purpose During a pathological inflammation, macrophages are activated to produce
accumulation of inflammatory mediators such as induced-cyclooxygenase-2 (COX-2), 15 …
accumulation of inflammatory mediators such as induced-cyclooxygenase-2 (COX-2), 15 …
The impact of cytokines in coronary atherosclerotic plaque: current therapeutic approaches
Coronary atherosclerosis is a chronic pathological process that involves inflammation
together with endothelial dysfunction and lipoprotein dysregulation. Experimental studies …
together with endothelial dysfunction and lipoprotein dysregulation. Experimental studies …
[HTML][HTML] Role of pro-inflammatory cytokines in Alzheimer's disease and neuroprotective effects of pegylated self-assembled nanoscaffolds
Neurodegeneration and synaptic loss in Alzheimer's disease (AD) lead to impairment in
memory functions. Neuroinflammation causes activation of microglia and astrocytes cells …
memory functions. Neuroinflammation causes activation of microglia and astrocytes cells …
An integrated cytokine and kynurenine network as the basis of neuroimmune communication
TW Stone, FIL Clanchy, YS Huang… - Frontiers in …, 2022 - frontiersin.org
Two of the molecular families closely associated with mediating communication between the
brain and immune system are cytokines and the kynurenine metabolites of tryptophan. Both …
brain and immune system are cytokines and the kynurenine metabolites of tryptophan. Both …