Bioelectric interface technologies in cells and organoids

Z Xue, J Zhao - Advanced Materials Interfaces, 2023 - Wiley Online Library
The past two decades have witnessed breakthroughs in cellular‐scale bioelectronics and
their widespread applications in life sciences, creating many powerful platforms for studying …

Combining PEDOT: PSS polymer coating with metallic 3D nanowires electrodes to achieve high electrochemical performances for neuronal interfacing applications

I Muguet, A Maziz, F Mathieu, L Mazenq… - Advanced …, 2023 - Wiley Online Library
This study presents a novel approach to improve the performance of microelectrode arrays
(MEAs) used for electrophysiological studies of neuronal networks. The integration of 3D …

Recent applications and prospects of nanowire-based biosensors

VA Tran, GNL Vo, TTT Vo, VD Doan, V Vo, VT Le - Processes, 2023 - mdpi.com
High-sensitivity biomedical sensors could make it possible to detect and classify chemical
and biological species in a variety of applications, from disease diagnosis to medication …

Nanocrown electrodes for parallel and robust intracellular recording of cardiomyocytes

Z Jahed, Y Yang, CT Tsai, EP Foster… - Nature …, 2022 - nature.com
Drug-induced cardiotoxicity arises primarily when a compound alters the
electrophysiological properties of cardiomyocytes. Features of intracellular action potentials …

Bioinspired two-in-one nanotransistor sensor for the simultaneous measurements of electrical and mechanical cellular responses

H Gao, F Yang, K Sattari, X Du, T Fu, S Fu, X Liu… - Science …, 2022 - science.org
The excitation-contraction dynamics in cardiac tissue are the most important physiological
parameters for assessing developmental state. We demonstrate integrated nanoelectronic …

Integrated cardiomyocyte-based biosensing platform for electroporation-triggered intracellular recording in parallel with delivery efficiency evaluation

J Fang, Y Pan, J Xu, D Xu, H Li, C Liu, N Hu - Nano Letters, 2023 - ACS Publications
Electroporation is a proven technique that can record action potential of cardiomyocytes and
serve for biomolecular delivery. To ensure high cell viability, micro-nanodevices cooperating …

Bone tissue engineering based on sustained release of MiR29c-modified framework nucleic acids from an injectable hydrogel

J Sun, Y Gao, Y Yao, Y Li, M Feng, L Bai… - Chemical Engineering …, 2024 - Elsevier
Bone defects affect the daily activities of patients and are prevalent complications of various
skeletal disorders. The miR29 family regulates bone physiology and pathological processes …

Transparent Intracellular Sensing Platform with Si Needles for Simultaneous Live Imaging

W Park, EM Kim, Y Jeon, J Lee, J Yi, J Jeong, B Kim… - ACS …, 2023 - ACS Publications
Vertically ordered Si needles are of particular interest for long-term intracellular recording
owing to their capacity to infiltrate living cells with negligible damage and minimal toxicity …

Engineered Nanotopographies Induce Transient Openings in the Nuclear Membrane

E Sarikhani, V Patel, Z Li… - Advanced Functional …, 2024 - Wiley Online Library
Materials with engineered nano‐scale surface topographies, such as nanopillars,
nanoneedles, and nanowires, mimic natural structures like viral spike proteins, enabling …

Repeated and on-demand intracellular recordings of cardiomyocytes derived from human-induced pluripotent stem cells

J Lee, T Ganswein, H Ulusan, V Emmenegger… - ACS …, 2022 - ACS Publications
Pharmaceutical compounds may have cardiotoxic properties, triggering potentially life-
threatening arrhythmias. To investigate proarrhythmic effects of drugs, the patch clamp …