Traumatic brain injury is a highly prevalent medical condition for which no medications
specific for the prophylaxis or treatment of the condition as a whole exist. The spectrum of …

An epilepsy diagnosis reduces a patient's quality of life tremendously, and it is a fate shared
by over 50 million people worldwide. Temporal lobe epilepsy (TLE) is largely considered a …

Traumatic brain injury leads to cellular and circuit changes in the dentate gyrus, a gateway
to hippocampal information processing. Intrinsic granule cell firing properties and strong …

Epilepsy is a chronic neurological disorder characterized by recurring, unprovoked seizures,
asymmetrical electroencephalogram patterns, and other pathological abnormalities. The …

Optogenetics has revolutionized the landscape of research on neurological disorders by
enabling high spatial specificity and millisecond-level temporal precision in neuroscience …

Post-traumatic epilepsy (PTE) is a serious consequence of traumatic brain injury (TBI). PTE
develops following a latent postinjury period during which alterations in neuronal network …

Adult Born Dentate Granule Cell Mediated Upregulation of Feedback Inhibition in a Mouse
Model of Traumatic Brain Injury Kang YJ, Lee SH, Boychuk JA, Butler CR, Juras JA, Cloyd …

Neuroimmune signals within the brain have a dual role in modulating neurophysiology both
at baseline and in response to injury and infection. The primary focus of existing literature is …

GABAergic interneurons. GABAergic cells regulate the flow of information in local neural
networks, affecting the excitability of glutamatergic cells, being responsible for filtering the …