Fluid mechanics of vascular systems, diseases, and thrombosis

DM Wootton, DN Ku - Annual review of biomedical engineering, 1999 - annualreviews.org
▪ Abstract The cardiovascular system is an internal flow loop with multiple branches
circulating a complex liquid. The hallmarks of blood flow in arteries are pulsatility and …

In vitro thrombogenicity testing of biomaterials

S Braune, RA Latour, M Reinthaler… - Advanced …, 2019 - Wiley Online Library
The short‐and long‐term thrombogenicity of implant materials is still unpredictable, which is
a significant challenge for the treatment of cardiovascular diseases. A knowledge‐based …

Microrheology of Erythrocytes and Thrombocytes, Blood Viscosity and the Distribution of Blood Flow in the Microcirculation

M Boutet, U Fuchs, P Gaehtgens, OH Gauer… - Mikrozirkulation …, 1977 - Springer
The influence of blood viscosity in the normal and abnormal physiology of the circulatory
system has long been neglected. In light of the overwhelming influence of vasomotor …

Platelet interaction with subendothelium in flowing rabbit blood: effect of blood shear rate

VT Turitto, HR Baumgartner - Microvascular research, 1979 - Elsevier
An annular perfusion chamber was utilized to expose subendothelium from everted rabbit
aorta to blood flowing under controlled conditions. Initial platelet contact (C), platelet …

The effects of flow on blood coagulation and thrombosis

SM Slack, Y Cui, VT Turitto - Thrombosis and haemostasis, 1993 - thieme-connect.com
Both hemostasis and its pathological correlate. thrombosis. are dynamic events. That is. the
various biochemical mechanisms that determine the extent of thrombosis at a particular site …

Are there sufficient standards for the in vitro hemocompatibility testing of biomaterials?

S Braune, M Grunze, A Straub, F Jung - Biointerphases, 2013 - Springer
1 Background The increasing age of populations in industrialized nations-together with a
lack of physical activity and changed diet habits-are associated with an increase of …

Identification of quantifiable hemodynamic factors in the assessment of cerebral aneurysm behavior on behalf of the subcommittee on biorheology of the scientific and …

AC Burleson, VT Turitto - Thrombosis and haemostasis, 1996 - thieme-connect.com
Previous experimental and theoretical studies on the hemodynamics of saccular intracranial
aneurysms have provided evidence that aneurysms tend to grow, thrombose and rupture …

Biological effects of dynamic shear stress in cardiovascular pathologies and devices

G Girdhar, D Bluestein - Expert review of medical devices, 2008 - Taylor & Francis
Altered and highly dynamic shear stress conditions have been implicated in endothelial
dysfunction leading to cardiovascular disease, and in thromboembolic complications in …

Properties of washed human platelets

RL Kinlough-Rathbone, JF Mustard… - Thrombosis and …, 1977 - thieme-connect.com
We have shown previously that washed human platelets resuspended in Tyrode solution
containing albumin and apyrase maintain their disc shape and their ability to aggregate …

Duration of exposure to high fluid shear stress is critical in shear-induced platelet activation-aggregation

Z Jian-ning, AL Bergeron, Q Yu, C Sun… - Thrombosis and …, 2003 - thieme-connect.com
Platelet functions are increasingly measured under flow conditions to account for blood
hydrodynamic effects. Typically, these studies involve exposing platelets to high shear stress …