Respiratory syncytial virus vaccines: a review of the candidates and the approved vaccines

X Topalidou, AM Kalergis, G Papazisis - Pathogens, 2023 - mdpi.com
Respiratory syncytial virus (RSV) is responsible for a significant proportion of global
morbidity and mortality affecting young children and older adults. In the aftermath of formalin …

Prevention and potential treatment strategies for respiratory Syncytial Virus

BW Sun, PP Zhang, ZH Wang, X Yao, ML He, RT Bai… - Molecules, 2024 - mdpi.com
Respiratory syncytial virus (RSV) is a significant viral pathogen that causes respiratory
infections in infants, the elderly, and immunocompromised individuals. RSV-related …

Structure and antigenicity of divergent Henipavirus fusion glycoproteins

A Isaacs, YS Low, KL Macauslane, J Seitanidou… - Nature …, 2023 - nature.com
In August 2022, a novel henipavirus (HNV) named Langya virus (LayV) was isolated from
patients with severe pneumonic disease in China. This virus is closely related to Mòjiāng …

Characterization and comparison of novel adjuvants for a prefusion clamped MERS vaccine

JS O'Donnell, A Isaacs, V Jakob, C Lebas… - Frontiers in …, 2022 - frontiersin.org
Various chemical adjuvants are available to augment immune responses to non-replicative,
subunit vaccines. Optimized adjuvant selection can ensure that vaccine-induced immune …

Key considerations to improve the normalization, interpretation and reproducibility of morbidity data in mammalian models of viral disease

JA Belser, TJ Kieran, ZA Mitchell… - Disease Models & …, 2024 - journals.biologists.com
Viral pathogenesis and therapeutic screening studies that utilize small mammalian models
rely on the accurate quantification and interpretation of morbidity measurements, such as …

The role of N-glycosylation in spike antigenicity for the SARS-CoV-2 gamma variant

CL Pegg, N Modhiran, RH Parry, B Liang… - …, 2024 - academic.oup.com
The emergence of SARS-CoV-2 variants alters the efficacy of existing immunity towards the
viral spike protein, whether acquired from infection or vaccination. Mutations that impact N …

[HTML][HTML] Respiratory syncytial virus: A new era

J Ruiz-Galiana, R Cantón, PDL Ramos… - Revista Española de …, 2024 - ncbi.nlm.nih.gov
Respiratory syncytial virus (RSV) is a major public health problem that has undergone
significant changes in recent years. First of all, it has become easier to diagnose with highly …

Lipid A-modified Escherichia coli can produce porcine parvovirus virus-like particles with high immunogenicity and minimal endotoxin activity

X Shen, YB Yang, Y Gao, S Wang, H Wang, M Sun… - Microbial Cell …, 2024 - Springer
Background A cost-effective Escherichia coli expression system has gained popularity for
producing virus-like particle (VLP) vaccines. However, the challenge lies in balancing the …

Vaccine process technology—A decade of progress

B Buckland, G Sanyal, T Ranheim… - Biotechnology and …, 2024 - Wiley Online Library
In the past decade, new approaches to the discovery and development of vaccines have
transformed the field. Advances during the COVID‐19 pandemic allowed the production of …

Development of subunit vaccine: A step forward toward cost-effective technology of vaccine candidate discovery

M Waseem, H Qureshi, K Maheen, M Kanwal… - Reverse …, 2024 - Elsevier
Subunit vaccines offer a potential method for vaccine discovery and are a more affordable
and secure alternative to conventional treatments. They do not pose a risk of side effects and …