Beyond the hippocampus and the SVZ: adult neurogenesis throughout the brain

MP Jurkowski, L Bettio, E K. Woo, A Patten… - Frontiers in cellular …, 2020 - frontiersin.org
Convincing evidence has repeatedly shown that new neurons are produced in the
mammalian brain into adulthood. Adult neurogenesis has been best described in the …

[HTML][HTML] Depression and adult neurogenesis: Positive effects of the antidepressant fluoxetine and of physical exercise

L Micheli, M Ceccarelli, G D'Andrea, F Tirone - Brain research bulletin, 2018 - Elsevier
Of wide interest for health is the relation existing between depression, a very common
psychological illness, accompanied by anxiety and reduced ability to concentrate, and adult …

Exercise is the real polypill

C Fiuza-Luces, N Garatachea, NA Berger… - Physiology, 2013 - journals.physiology.org
The concept of a “polypill” is receiving growing attention to prevent cardiovascular disease.
Yet similar if not overall higher benefits are achievable with regular exercise, a drug-free …

Physical exercise-induced hippocampal neurogenesis and antidepressant effects are mediated by the adipocyte hormone adiponectin

SY Yau, A Li, RLC Hoo, YP Ching… - Proceedings of the …, 2014 - National Acad Sciences
Adiponectin (ADN) is an adipocyte-secreted protein with insulin-sensitizing, antidiabetic,
antiinflammatory, and antiatherogenic properties. Evidence is also accumulating that ADN …

Abnormal hippocampal BDNF and miR-16 expression is associated with depression-like behaviors induced by stress during early life

M Bai, X Zhu, Y Zhang, S Zhang, L Zhang, L Xue, J Yi… - 2012 - journals.plos.org
Some environmental stressors lead to the onset of depression via inhibiting hippocampal
BDNF expression, but other environmental stressors-induced depression exhibits no …

Effects of physical exercise on depressive symptoms and biomarkers in depression

T Archer, T Josefsson, M Lindwall - CNS & Neurological …, 2014 - ingentaconnect.com
Regular physical exercise/activity has been shown repeatedly to promote positive benefits in
cognitive, emotional and motor domains concomitant with reductions in distress and …

Adult neurogenesis: a substrate for experience-dependent change

M Opendak, E Gould - Trends in cognitive sciences, 2015 - cell.com
A rapidly growing body of literature indicates that adult neurogenesis in the hippocampus is
sensitive to a variety of environmental factors. The effects of emotionally salient experiences …

[HTML][HTML] Physical activity in depressed elderly. A systematic review

G Mura, MG Carta - Clinical practice and epidemiology in mental …, 2013 - ncbi.nlm.nih.gov
Background: exercise may reduce depressive symptoms both in healthy aged populations
and in old patients diagnosed with MDD, but few specific analysis were conducted on the …

Long-term mild, rather than intense, exercise enhances adult hippocampal neurogenesis and greatly changes the transcriptomic profile of the hippocampus

K Inoue, M Okamoto, J Shibato, MC Lee, T Matsui… - PloS one, 2015 - journals.plos.org
Our six-week treadmill running training (forced exercise) model has revealed that mild
exercise (ME) with an intensity below the lactate threshold (LT) is sufficient to enhance …

Physical exercise‐induced adult neurogenesis: a good strategy to prevent cognitive decline in neurodegenerative diseases?

S Yau, J Gil-Mohapel, BR Christie… - BioMed research …, 2014 - Wiley Online Library
Cumulative evidence has indicated that there is an important role for adult hippocampal
neurogenesis in cognitive function. With the increasing prevalence of cognitive decline …