Anti-cancer palladium complexes: a focus on PdX 2 L 2, palladacycles and related complexes
AR Kapdi, IJS Fairlamb - Chemical Society Reviews, 2014 - pubs.rsc.org
Much success has been achieved with platinum-based chemotherapeutic agents, ie through
interactions with DNA. The long-term application of Pt complexes is thwarted by issues …
interactions with DNA. The long-term application of Pt complexes is thwarted by issues …
Anticancer cyclometalated complexes of platinum group metals and gold
N Cutillas, GS Yellol, C de Haro, C Vicente… - Coordination chemistry …, 2013 - Elsevier
The clinical success of cisplatin and its derivatives has had an enormous impact on the
discovery of novel metal-based drugs. Extensive studies have focused on the interaction of …
discovery of novel metal-based drugs. Extensive studies have focused on the interaction of …
Organometallic compounds: an opportunity for chemical biology?
Organometallic compounds are renowned for their remarkable applications in the field of
catalysis, but much less is known about their potential in chemical biology. Indeed, such …
catalysis, but much less is known about their potential in chemical biology. Indeed, such …
[HTML][HTML] Revisiting metallodrugs for the treatment of skin cancers
CM Manzano, DH Nakahata, REF de Paiva - Coordination Chemistry …, 2022 - Elsevier
Metallodrugs were classically screened against skin cancer (either in vitro or in vivo) at the
peak of the development of platinum anticancer agents. New systematic studies appeared in …
peak of the development of platinum anticancer agents. New systematic studies appeared in …
Organometallic palladium complexes with a water-soluble iminophosphorane ligand as potential anticancer agents
M Carreira, R Calvo-Sanjuan, M Sanau, I Marzo… - …, 2012 - ACS Publications
The synthesis and characterization of a new water-soluble iminophosphorane ligand TPA
NC (O)-2BrC6H4 (1, C, N-IM; TPA= 1, 3, 5-triaza-7-phosphaadamantane) is reported …
NC (O)-2BrC6H4 (1, C, N-IM; TPA= 1, 3, 5-triaza-7-phosphaadamantane) is reported …
Transfer hydrogenation and antiproliferative activity of tethered half-sandwich organoruthenium catalysts
F Chen, I Romero-Canelón, JJ Soldevila-Barreda… - …, 2018 - ACS Publications
We report the synthesis and characterization of four neutral organometallic tethered
complexes,[Ru (η6-Ph (CH2) 3-ethylenediamine-NR) Cl], where R= methanesulfonyl (Ms …
complexes,[Ru (η6-Ph (CH2) 3-ethylenediamine-NR) Cl], where R= methanesulfonyl (Ms …
1, 4-benzodiazepin-2-ones in medicinal chemistry
J Spencer, RP Rathnam… - Future Medicinal Chemistry, 2010 - Taylor & Francis
1, 4-benzodiazepin-2-ones have applications in many areas of medicinal chemistry that are
not restricted to 'classical'CNS treatments such as sedatives, epilepsy and muscle relaxants …
not restricted to 'classical'CNS treatments such as sedatives, epilepsy and muscle relaxants …
Efficacy of a binuclear cyclopalladated compound therapy for cutaneous leishmaniasis in the murine model of infection with Leishmania amazonensis and its …
AMA Velásquez, WC Ribeiro, V Venn… - Antimicrobial agents …, 2017 - Am Soc Microbiol
Leishmaniasis is a disease found throughout the (sub) tropical parts of the world caused by
protozoan parasites of the Leishmania genus. Despite the numerous problems associated …
protozoan parasites of the Leishmania genus. Despite the numerous problems associated …
An expedient approach to substituted triazolo [1, 5-a][1, 4] benzodiazepines via Cu-catalyzed tandem Ullmann C–N coupling/azide-alkyne cycloaddition
KC Majumdar, S Ganai - Tetrahedron letters, 2013 - Elsevier
An approach to the synthesis of triazolo [1, 5-a][1, 4] benzodiazepines comprising copper
catalyzed tandem Ullmann C–N coupling followed by azide-alkyne cycloaddition has been …
catalyzed tandem Ullmann C–N coupling followed by azide-alkyne cycloaddition has been …
Cyclopalladated compounds containing 2, 6-lutidine: Synthesis, spectral and biological studies
GA da Cunha, RFF de Souza, RL de Farias… - Journal of Inorganic …, 2020 - Elsevier
Bridge splitting reactions between [Pd (C 2, N-dmba)(μ-X)] 2 (dmba= N, N-
dimethylbenzylamine; X= Cl, I, N 3, NCO) and 2, 6-lutidine (lut) in the 1: 2 molar ratio at room …
dimethylbenzylamine; X= Cl, I, N 3, NCO) and 2, 6-lutidine (lut) in the 1: 2 molar ratio at room …