Microbial biofilm: a review on formation, infection, antibiotic resistance, control measures, and innovative treatment

S Sharma, J Mohler, SD Mahajan, SA Schwartz… - Microorganisms, 2023 - mdpi.com
Biofilm is complex and consists of bacterial colonies that reside in an exopolysaccharide
matrix that attaches to foreign surfaces in a living organism. Biofilm frequently leads to …

Staphylococcus Epidermidis as a Cause of Bacteremia

S Kleinschmidt, F Huygens, J Faoagali… - Future …, 2015 - Taylor & Francis
Staphylococcus epidermidis is a biofilm-producing commensal organism found ubiquitously
on human skin and mucous membranes, as well as on animals and in the environment …

Biofilm formation of methicillin-resistant coagulase negative staphylococci (MR-CoNS) isolated from community and hospital environments

R Seng, T Kitti, R Thummeepak, P Kongthai… - PloS one, 2017 - journals.plos.org
Methicillin-resistant coagulase negative staphylococci (MR-CoNS) are the major cause of
infectious diseases because of their potential ability to form biofilm and colonize the …

Comparative evaluation of methods for the detection of biofilm formation in coagulase-negative staphylococci and correlation with antibiogram

LB Shrestha, NR Bhattarai, B Khanal - Infection and drug …, 2018 - Taylor & Francis
Introduction: Coagulase-negative staphylococci (CNS) are normal commensals of human
skin and mucous membranes. The objective of the study was to determine the prevalence of …

Alginate and chitosan-based hydrogel enhance antibacterial agent activity on topical application

N Wathoni, C Suhandi… - Infection and Drug …, 2024 - Taylor & Francis
Untreated topical infections can become chronic, posing serious health issues. Optimal skin
adherence is crucial in addressing such infections. In this context, chitosan and alginate …

MBD2 upregulates miR-301a-5p to induce kidney cell apoptosis during vancomycin-induced AKI

J Wang, H Li, S Qiu, Z Dong, X Xiang, D Zhang - Cell death & disease, 2017 - nature.com
Despite DNA methylation occurred in acute kidney injury (AKI), how it influenced
progression of AKI remains unclear. Methyl-CpG-binding domain protein 2 (MBD2), a …

Identification of hemolysin encoding genes and their association with antimicrobial resistance pattern among clinical isolates of coagulase-negative Staphylococci

M Nasaj, Z Saeidi, B Asghari, G Roshanaei… - BMC research …, 2020 - Springer
Abstract Objective Coagulase-negative staphylococci (CoNS) are as considered
opportunistic pathogens which capable of producing several toxins, enzymes and resistance …

Antimicrobial resistance and virulence determinants in coagulase-negative staphylococci isolated mainly from preterm neonates

A Al-Haqan, SS Boswihi, S Pathan, EE Udo - PLoS One, 2020 - journals.plos.org
Coagulase-negative staphylococci (CoNS) are the most common isolates from blood culture
in neonates resulting in high mortality and morbidity. This study investigated CoNS obtained …

Phenylthiazoles with tert-Butyl side chain: Metabolically stable with anti-biofilm activity

A Kotb, NS Abutaleb, MA Seleem, M Hagras… - European journal of …, 2018 - Elsevier
A new series of phenylthiazoles with t-butyl lipophilic component was synthesized and their
antibacterial activity against a panel of multidrug-resistant bacterial pathogens was …

p53 activates miR-192-5p to mediate vancomycin induced AKI

J Chen, J Wang, H Li, S Wang, X Xiang, D Zhang - Scientific reports, 2016 - nature.com
Pathogenic role of p53 in AKI remains controversial and the underlying mechanism is
unclear. Here, we tested whether the inhibition of p53 may ameliorate vancomycin (VAN) …