Long non-coding RNAs in lung cancer: Unraveling the molecular modulators of MAPK signaling
Lung cancer (LC) continues to pose a significant global medical burden, necessitating a
comprehensive understanding of its molecular foundations to establish effective treatment …
comprehensive understanding of its molecular foundations to establish effective treatment …
[HTML][HTML] Long non-coding RNA NEAT1: a novel target for diagnosis and therapy in human tumors
P Dong, Y Xiong, J Yue, SJB Hanley… - Frontiers in …, 2018 - frontiersin.org
The nuclear paraspeckle assembly transcript 1 (NEAT1, a long non-coding RNA) is
frequently overexpressed in human tumors, and higher NEAT1 expression is correlated with …
frequently overexpressed in human tumors, and higher NEAT1 expression is correlated with …
p53 induces formation of NEAT1 lncRNA-containing paraspeckles that modulate replication stress response and chemosensitivity
C Adriaens, L Standaert, J Barra, M Latil, A Verfaillie… - Nature medicine, 2016 - nature.com
In a search for mediators of the p53 tumor suppressor pathway, which induces pleiotropic
and often antagonistic cellular responses, we identified the long noncoding RNA (lncRNA) …
and often antagonistic cellular responses, we identified the long noncoding RNA (lncRNA) …
NEAT 1: A novel cancer‐related long non‐coding RNA
X Yu, Z Li, H Zheng, MTV Chan, WKK Wu - Cell proliferation, 2017 - Wiley Online Library
Aberrant overexpression of the long non‐coding RNA NEAT 1 (nuclear paraspeckle
assembly transcript 1) has been documented in different types of solid tumours, such as lung …
assembly transcript 1) has been documented in different types of solid tumours, such as lung …
[HTML][HTML] Long non-coding RNA NEAT1 promotes non-small cell lung cancer progression through regulation of miR-377-3p-E2F3 pathway
Recently, the long non-coding RNA (lncRNA) NEAT1 has been identified as an oncogenic
gene in multiple cancer types and elevated expression of NEAT1 was tightly linked to …
gene in multiple cancer types and elevated expression of NEAT1 was tightly linked to …
From junk to master regulators of invasion: lncRNA functions in migration, EMT and metastasis
S Dhamija, S Diederichs - International journal of cancer, 2016 - Wiley Online Library
Metastasis is a multistep process that involves the dissemination of cells from the primary
tumor and colonization of distant secondary organs. Epithelial cells at the invasive front of a …
tumor and colonization of distant secondary organs. Epithelial cells at the invasive front of a …
[HTML][HTML] Oct4 transcriptionally regulates the expression of long non-coding RNAs NEAT1 and MALAT1 to promote lung cancer progression
Background Oct4, a key stemness transcription factor, is overexpressed in lung cancer.
Here, we reveal a novel transcription regulation of long non-coding RNAs (lncRNAs) by …
Here, we reveal a novel transcription regulation of long non-coding RNAs (lncRNAs) by …
[HTML][HTML] Long noncoding RNA NEAT1 promotes laryngeal squamous cell cancer through regulating miR-107/CDK6 pathway
P Wang, T Wu, H Zhou, Q Jin, G He, H Yu… - Journal of experimental …, 2016 - Springer
Background Long noncoding RNA nuclear paraspeckle assembly transcript 1 (NEAT1)
plays key role in the progression of some human cancers. However, the role of NEAT1 in …
plays key role in the progression of some human cancers. However, the role of NEAT1 in …
Long non-coding RNA NEAT1 regulates ferroptosis sensitivity in non-small-cell lung cancer
H Wu, A Liu - Journal of International Medical Research, 2021 - journals.sagepub.com
Objectives Ferroptosis is caused by iron-dependent lipid peroxide accumulation, the
sensitivity of which might be regulated by acyl-CoA synthetase long chain family member 4 …
sensitivity of which might be regulated by acyl-CoA synthetase long chain family member 4 …
[HTML][HTML] Long noncoding RNA NEAT1 promotes cardiac fibrosis in heart failure through increased recruitment of EZH2 to the Smad7 promoter region
Z Ge, C Yin, Y Li, D Tian, Y Xiang, Q Li, Y Tang… - Journal of translational …, 2022 - Springer
Cardiac fibrosis, a well-known major pathological process that ultimately leads to heart
failure, has attracted increasing attention and focus in recent years. A large amount of …
failure, has attracted increasing attention and focus in recent years. A large amount of …