Saponins are bioactive compounds generally considered to be produced by plants to
counteract pathogens and herbivores. Besides their role in plant defense, saponins are of …

Triterpenes are compounds of natural origin, which have numerously biological activities:
anti-cancer properties, anti-inflammatory, anti-oxidative, anti-viral, anti-bacterial and anti …

The saponins are a diverse class of natural products, with a broad scale distribution across
different plant species. Chemically characterized as triterpenoid glycosides, they posses a …

Introduction: Betulinic acid (BA) is a triterpenoid that can be obtained from renewable
resources. BA is cytotoxic to many human tumor cell lines mainly by apoptosis but cell death …

Saponins are bioactive compounds produced mainly by plants but also by some marine
organisms and insects. In the recent past, there has been unforeseen interest in the clinical …

Saponins are a large family of amphiphilic glycosides of steroids and triterpenes found in
plants and some marine organisms. By expressing a large diversity of structures on both …

This review covers the chemistry of allobetulin analogs, including their formation by
rearrangement from betulin derivatives, their further derivatisation, their fusion with …

The sustainable development of an emergent country is dependent on a consistent
scientific, technologic and innovative policy, on nature and biodiversity, on a rational …

Protein-based targeted toxins play an increasingly important role in targeted tumor
therapies. In spite of their high intrinsic toxicity, their efficacy in animal models is low. A major …

A convenient synthesis is presented for a new class of bioactive bifunctionalized conjugates
of lupane-type triterpenoids with triphenylphosphonium (TPP) and glycopyranosyl targeting …