Breakthroughs in materials engineering have accelerated the progress of immunotherapy in
preclinical studies. The interplay of chemistry and materials has resulted in improved …

It was discovered almost 20 years ago that plasmid DNA, when injected into the skin or
muscle of mice, could induce immune responses to encoded antigens. Since that time, there …

This review provides a detailed look at the attributes and immunologic mechanisms of
plasmid DNA vaccines and their utility as laboratory tools as well as potential human …

Nanocarriers with various compositions and biological properties have been extensively
applied for in vitro/in vivo drug and gene delivery. The family of nanocarriers includes …

Despite many years of research, human DNA vaccines have yet to fulfill their early promise.
Over the past 15 years, multiple generations of DNA vaccines have been developed and …

A subset of human papillomaviruses (HPVs) promote anogenital malignancy, including
cervical cancer, and prevention and treatment strategies that reflect the causal role of HPV …

Purpose: The study aims to evaluate the effect of a human papillomavirus type 16 (HPV16)
E6 and E7 synthetic long peptides vaccine on the antigen-specific T-cell response in …

DNA vaccination has suddenly become a favoured strategy for inducing immunity. The
molecular precision offered by gene-based vaccines, together with the facility to include …

Abstract Development of HPV-associated cancers not only depends on efficient negative
regulation of cell cycle control that supports the accumulation of genetic damage, but also …

Individuals with human immunodeficiency virus (HIV) infection are at increased risk for
human papillomavirus—related squamous cell cancer of the anus. Screening HIV-infected …