[HTML][HTML] Tandem repeats mediating genetic plasticity in health and disease
AJ Hannan - Nature Reviews Genetics, 2018 - nature.com
Accumulating evidence suggests that many classes of DNA repeats exhibit attributes that
distinguish them from other genetic variants, including the fact that they are more liable to …
distinguish them from other genetic variants, including the fact that they are more liable to …
Repetitive DNA sequence detection and its role in the human genome
Repetitive DNA sequences playing critical roles in driving evolution, inducing variation, and
regulating gene expression. In this review, we summarized the definition, arrangement, and …
regulating gene expression. In this review, we summarized the definition, arrangement, and …
Short tandem repeats bind transcription factors to tune eukaryotic gene expression
CA Horton, AM Alexandari, MGB Hayes, E Marklund… - Science, 2023 - science.org
Short tandem repeats (STRs) are enriched in eukaryotic cis-regulatory elements and alter
gene expression, yet how they regulate transcription remains unknown. We found that STRs …
gene expression, yet how they regulate transcription remains unknown. We found that STRs …
Challenges in analysis and interpretation of microsatellite data for population genetic studies
Advancing technologies have facilitated the ever‐widening application of genetic markers
such as microsatellites into new systems and research questions in biology. In light of the …
such as microsatellites into new systems and research questions in biology. In light of the …
[HTML][HTML] Abundant contribution of short tandem repeats to gene expression variation in humans
The contribution of repetitive elements to quantitative human traits is largely unknown. Here
we report a genome-wide survey of the contribution of short tandem repeats (STRs), which …
we report a genome-wide survey of the contribution of short tandem repeats (STRs), which …
Forensic autosomal short tandem repeats and their potential association with phenotype
Forensic DNA profiling utilizes autosomal short tandem repeat (STR) markers to establish
identity of missing persons, confirm familial relations, and link persons of interest to crime …
identity of missing persons, confirm familial relations, and link persons of interest to crime …
Mutation and selection processes regulating short tandem repeats give rise to genetic and phenotypic diversity across species
M Verbiest, M Maksimov, Y Jin… - Journal of …, 2023 - academic.oup.com
Short tandem repeats (STRs) are units of 1–6 bp that repeat in a tandem fashion in DNA.
Along with single nucleotide polymorphisms and large structural variations, they are among …
Along with single nucleotide polymorphisms and large structural variations, they are among …
An improved genome assembly uncovers prolific tandem repeats in Atlantic cod
Abstract Background The first Atlantic cod (Gadus morhua) genome assembly published in
2011 was one of the early genome assemblies exclusively based on high-throughput 454 …
2011 was one of the early genome assemblies exclusively based on high-throughput 454 …
Functional mechanisms of microsatellite DNA in eukaryotic genomes
ATM Bagshaw - Genome biology and evolution, 2017 - academic.oup.com
Microsatellite repeat DNA is best known for its length mutability, which is implicated in
several neurological diseases and cancers, and often exploited as a genetic marker. Less …
several neurological diseases and cancers, and often exploited as a genetic marker. Less …
A genomic view of short tandem repeats
M Gymrek - Current opinion in genetics & development, 2017 - Elsevier
Short tandem repeats (STRs) are some of the fastest mutating loci in the genome. Tools for
accurately profiling STRs from high-throughput sequencing data have enabled genome …
accurately profiling STRs from high-throughput sequencing data have enabled genome …