The efficiency, selectivity and sustainability benefits offered by enzymes are enticing
chemists to consider biocatalytic transformations to complement or even supplant more …

Recent developments of stereoselective biocatalytic and chemocatalytic methods are
discussed. The review provides a guide to the use of biocatalytic methods in the area of …

We developed an efficient visible-light-mediated formal carbene insertion reaction of 1, 3-
diketones with diazoesters for the construction of enantioenriched 1, 4-dicarbonyl …

Carbon–carbon bond formation is the key reaction for organic synthesis to construct the
carbon framework of organic molecules. The review gives a selection of biocatalytic C–C …

The prodiginine family of bacterial alkaloids is a diverse set of heterocyclic natural products
that have likely been known to man since antiquity. In more recent times, these alkaloids …

Despite the astonishing breadth of enzymes in nature, no enzymes are known for many of
the valuable catalytic transformations discovered by chemists. Recent work in enzyme …

PROTONtype: An NHC‐catalyzed (NHC= N‐heterocyclic carbene), highly asymmetric
intermolecular Stetter reaction allows the atom‐economic and efficient formation of valuable …

An asymmetric intermolecular Stetter reaction of enals with nitroalkenes catalyzed by chiral
N-heterocyclic carbenes has been developed. The reaction rate and efficiency are …

N-Heterocyclic carbene (NHC)-catalyzed umpolung reactions [1] offer an elegant access to
several important classes of compounds, such as benzoins [2] or g-butyrolactones.[3] In …

Enzymes, at the turn of the 21st century, are gaining a momentum. Especially in the field of
synthetic organic chemistry, a broad variety of biocatalysts are being applied in an …