Transposable elements: genome innovation, chromosome diversity, and centromere conflict
SJ Klein, RJ O'Neill - Chromosome Research, 2018 - Springer
Although it was nearly 70 years ago when transposable elements (TEs) were first
discovered “jumping” from one genomic location to another, TEs are now recognized as …
discovered “jumping” from one genomic location to another, TEs are now recognized as …
Origin and functional role of antisense transcription in endogenous and exogenous retroviruses
F Romerio - Retrovirology, 2023 - Springer
Most proteins expressed by endogenous and exogenous retroviruses are encoded in the
sense (positive) strand of the genome and are under the control of regulatory elements …
sense (positive) strand of the genome and are under the control of regulatory elements …
Orientation-dependent regulation of integrated HIV-1 expression by host gene transcriptional readthrough
Y Han, YB Lin, W An, J Xu, HC Yang, K O'Connell… - Cell host & …, 2008 - cell.com
Integrated HIV-1 genomes are found within actively transcribed host genes in latently
infected CD4+ T cells. Readthrough transcription of the host gene might therefore suppress …
infected CD4+ T cells. Readthrough transcription of the host gene might therefore suppress …
Multifaceted mammalian transcriptome
P Carninci, J Yasuda, Y Hayashizaki - Current opinion in cell biology, 2008 - Elsevier
Despite surprisingly a small number of protein-coding gene in mammalian genomes, a large
variety of different RNAs is being produced. These RNAs are amazingly different in their …
variety of different RNAs is being produced. These RNAs are amazingly different in their …
Human endogenous retroviruses and the nervous system
RN Douville, A Nath - Handbook of clinical neurology, 2014 - Elsevier
Within the human genome reside thousands of retrovirus-like sequences which comprise
nearly 8% of the human genome. Originating from ancient retroviruses that overcame host …
nearly 8% of the human genome. Originating from ancient retroviruses that overcame host …
Regulation of Emx2 Expression by Antisense Transcripts in Murine Cortico-Cerebral Precursors
G Spigoni, C Gedressi, A Mallamaci - PloS one, 2010 - journals.plos.org
Background Emx2 encodes for a transcription factor expressed in the embryonic
intermediate mesoderm and central nervous system (CNS). It is implicated in several …
intermediate mesoderm and central nervous system (CNS). It is implicated in several …
[HTML][HTML] EBV LMP-2A employs a novel mechanism to transactivate the HERV-K18 superantigen through its ITAM
FC Hsiao, AK Tai, A Deglon, N Sutkowski… - Virology, 2009 - Elsevier
EBV encodes latent membrane protein (LMP)-2A that functions as a homologue of the
activated BCR. We have previously shown that LMP-2A transactivates a human …
activated BCR. We have previously shown that LMP-2A transactivates a human …
Intronic L1 retrotransposons and nested genes cause transcriptional interference by inducing intron retention, exonization and cryptic polyadenylation
K Kaer, J Branovets, A Hallikma, P Nigumann… - PLoS …, 2011 - journals.plos.org
Background Transcriptional interference has been recently recognized as an unexpectedly
complex and mostly negative regulation of genes. Despite a relatively few studies that …
complex and mostly negative regulation of genes. Despite a relatively few studies that …
Evolutionary Conservation of Orthoretroviral Long Terminal Repeats (LTRs) and ab initio Detection of Single LTRs in Genomic Data
Background Retroviral LTRs, paired or single, influence the transcription of both retroviral
and non-retroviral genomic sequences. Vertebrate genomes contain many thousand …
and non-retroviral genomic sequences. Vertebrate genomes contain many thousand …
Evolution of closely linked gene pairs in vertebrate genomes
The orientation of closely linked genes in mammalian genomes is not random: there are
more head-to-head (h2h) gene pairs than expected. To understand the origin of this …
more head-to-head (h2h) gene pairs than expected. To understand the origin of this …