Renin-angiotensin-aldosterone system (RAAS) is a vital system of human body, as it
maintains plasma sodium concentration, arterial blood pressure and extracellular volume …

Epidemiologic data indicate that obesity increases the prevalence and incidence of asthma
and reduces asthma control. Obese mice exhibit innate airway hyperresponsiveness and …

Hypertension (HTN) is the medical term for high blood pressure. It is dangerous because it
makes the heart work too hard and contributes to atherosclerosis (hardening of arteries) …

Recent studies suggest that adipose tissue hypoxia (ATH) may contribute to endocrine
dysfunction in adipose tissue of obese mice. In this study, we examined hypoxia's effects on …

Background and aim Epidemiological data has established increasing adiposity as a risk
factor for incident asthma. However, the mechanisms underlying the association between …

A growing amount of epidemiological data from multiple countries indicate an increased
prevalence of obesity, more importantly central obesity, among hospitalized subjects with …

A local renin-angiotensin system (RAS) has been proposed in adipocytes. Adipocytes are a
suggested source of components of the RAS, with regulation of their production related to …

Excess food intake leads to obesity and diabetes, both of which are well-known independent
risk factors for atherosclerosis, and both of which are growing epidemics in an aging …

Activation of the renin‐angiotensin‐aldosterone system (RAAS) is the primary etiologic
event in the development of hypertension in people with diabetes mellitus. Modulation of the …

Atherosclerosis is an aging disease in which increasing age is a risk factor. Modified low-
density lipoprotein (LDL) is a well-known risk marker for cardiovascular disease. High …