Reactive nitrogen species and male reproduction: Physiological and pathological aspects

S Dutta, P Sengupta, S Das, P Slama… - International Journal of …, 2022 - mdpi.com
Reactive nitrogen species (RNS), like reactive oxygen species (ROS), are useful for
sustaining reproductive processes such as cell signaling, the regulation of hormonal …

Free radical and superoxide reactivity detection in semen quality assessment: past, present, and future

J Gosalvez, E Tvrda, A Agarwal - Journal of assisted reproduction and …, 2017 - Springer
Oxidative stress is a well-established cause of male infertility, with reactive oxygen species
(ROS) impairing sperm production, motility, membrane, and DNA integrity. Currently, most …

[HTML][HTML] Sperm viability, apoptosis, and intracellular reactive oxygen species levels in human spermatozoa before and after induction of oxidative stress

RZ Mahfouz, SS du Plessis, N Aziz, R Sharma… - Fertility and sterility, 2010 - Elsevier
OBJECTIVE: To investigate sperm viability, incidence of apoptosis, and intracellular basal
and induced reactive oxygen species (ROS) in sperm fractions. DESIGN: Prospective …

Reactive oxygen species and sperm DNA damage in infertile men presenting with low level leukocytospermia

A Agarwal, A Mulgund, S Alshahrani, M Assidi… - Reproductive biology …, 2014 - Springer
Background Leukocytes contribute directly and indirectly to reactive oxygen species (ROS)
production. Although leukocytospermia is defined as the presence of≥ 1× 10 6 white blood …

The exome sequencing identified the mutation in YARS2 encoding the mitochondrial tyrosyl-tRNA synthetase as a nuclear modifier for the phenotypic manifestation of …

P Jiang, X Jin, Y Peng, M Wang, H Liu… - Human Molecular …, 2016 - academic.oup.com
Leber's hereditary optic neuropathy (LHON) is the most common mitochondrial disorder.
Nuclear modifier genes are proposed to modify the phenotypic expression of LHON …

A deafness-associated tRNAHis mutation alters the mitochondrial function, ROS production and membrane potential

S Gong, Y Peng, P Jiang, M Wang, M Fan… - Nucleic acids …, 2014 - academic.oup.com
In this report, we investigated the molecular genetic mechanism underlying the deafness-
associated mitochondrial tRNAHis 12201T> C mutation. The destabilization of a highly …

Probiotic administration improves sperm quality in asthenozoospermic human donors

DG Valcarce, S Genovés, MF Riesco… - Beneficial …, 2017 - wageningenacademic.com
The objective of this study is to analyse the effect of the ingestion of two selected antioxidant
probiotics strains (Lactobacillus rhamnosus CECT8361 and Bifidobacterium longum …

Maternally Inherited Essential Hypertension Is Associated With the Novel 4263A>G Mutation in the Mitochondrial tRNAIle Gene in a Large Han Chinese Family

S Wang, R Li, A Fettermann, Z Li, Y Qian, Y Liu… - Circulation …, 2011 - Am Heart Assoc
Rational: Despite maternal transmission of hypertension in some pedigrees,
pathophysiology of maternally inherited hypertension remains poorly understood. Objective …

Effects of cryopreservation on phosphatidylserine translocation, intracellular hydrogen peroxide, and DNA integrity in canine sperm

SH Kim, DH Yu, YJ Kim - Theriogenology, 2010 - Elsevier
Evaluating cryoinjury of canine spermatozoa is crucial to improving the probability of
fertilization. Recently, studies on sperm ROS production, phospholipid scrambling, and DNA …

Evaluation of lasting effects of heat stress on sperm profile and oxidative status of ram semen and epididymal sperm

TRS Hamilton, CM Mendes, LS Castro… - Oxidative Medicine …, 2016 - Wiley Online Library
Higher temperatures lead to an increase of testicular metabolism that results in spermatic
damage. Oxidative stress is the main factor responsible for testicular damage caused by …