Potential drivers for the re-emergence of canine leptospirosis in the United States and Canada

AM Smith, JW Stull, GE Moore - Tropical Medicine and Infectious Disease, 2022 - mdpi.com
Canine leptospirosis is an important zoonotic disease in many countries. This review
examines potential drivers for increased diagnoses of canine leptospirosis in the United …

Updated ACVIM consensus statement on leptospirosis in dogs

JE Sykes, T Francey, S Schuller… - Journal of veterinary …, 2023 - Wiley Online Library
Since publication of the last consensus statement on leptospirosis in dogs, there has been
revision of leptospiral taxonomy and advancements in typing methods, widespread use of …

Time for change? A systematic review with meta-analysis of leptospires infecting dogs to assess vaccine compatibility in Brazil

SB Esteves, CM Santos, BCS Silva, FF Salgado… - Preventive Veterinary …, 2023 - Elsevier
Dogs are thought to be highly exposed to environmental pathogenic leptospires, possibly
acting as potential sources of infection for zoonotic transmission. Vaccination stands as the …

Seroprevalence of pathogenic Leptospira serogroups in asymptomatic domestic dogs and cats: systematic review and meta-analysis

T Ricardo, LI Azócar-Aedo, MA Previtali… - Frontiers in Veterinary …, 2024 - frontiersin.org
Leptospirosis is a neglected zoonotic disease transmitted by contact with the urine of
animals infected with pathogenic species of the bacteria Leptospira or by contact with …

Effect of Vaccination against Leptospira on Shelter Asymptomatic Dogs Following a Long-Term Study

R Sant'Anna da Costa, MIN Di Azevedo… - Animals, 2022 - mdpi.com
Simple Summary Dogs are known as hosts of Leptospira interrogans and can become
asymptomatic carriers of leptospires in the urine, spreading this bacterium to the …

The role of asymptomatic cattle for leptospirosis dynamics in a herd with imperfect vaccination

AG Regassa, LL Obsu - Scientific Reports, 2024 - nature.com
Leptospirosis is an emerging zoonotic disease with high health and economic damage. In
this study, we developed a deterministic mathematical model that describes the dynamics of …

Comparison of the PF07598-Encoded Virulence-Modifying Proteins of L. interrogans and L. borgpetersenii

DS Vieira, R Chaurasia, JM Vinetz - Tropical Medicine and Infectious …, 2022 - mdpi.com
Leptospirosis is an emerging infectious disease, with increasing frequency and severity of
outbreaks, a changing epidemiology of populations at risk, and the emergence of new …

Blocking pathogenic Leptospira invasion with aptamer molecules targeting outer membrane LipL32 protein

SH Hsu, HY Yang, CC Chang, SK Tsai, C Li… - Microbes and …, 2024 - Elsevier
This study aimed to develop aptamers targeting LipL32, a most abundant lipoprotein in
pathogenic Leptospira, to hinder bacterial invasion. The objectives were to identify high …

Canine leptospirosis: A One Health approach for improved surveillance, prevention, and interdisciplinary collaboration

CM Vyn, KC Libera, CM Jardine… - The Canadian …, 2024 - pmc.ncbi.nlm.nih.gov
Leptospirosis is a global zoonotic disease that causes morbidity and mortality in dogs,
humans, and other mammals (1). This disease is caused by pathogenic bacteria of the …

Evaluation of protective efficacy, serological responses, and cytokine modulation induced by polyvalent Leptospira vaccines in hamsters

NR de Oliveira, MAC Maia, FDS Santos… - … and Infectious Diseases, 2024 - Elsevier
Whole-cell inactivated vaccines (bacterins) are the only licensed vaccines available for
leptospirosis prevention and control, especially in domestic and farm animals. However …