Epigenetic inheritance and its underlying molecular mechanisms are among the most
intriguing areas of current biological and medical research. To date, studies have shown that …

Background: Bisphenol A (BPA) is an endocrine disrupting chemical widely used in the
manufacture of polycarbonate plastic and epoxy resin to produce a multitude of consumer …

Epigenetics is the branch of genetics that studies the different mechanisms that influence
gene expression without direct modification of the DNA sequence. An ever-increasing …

Inherited microorganisms can selfishly manipulate host reproduction to drive through
populations. In Drosophila melanogaster, germline expression of the native Wolbachia …

Objective To compare the microRNA (miRNA) expression profile in spermatozoa from three
infertile populations vs. a group of fertile men. Design Evaluation of the expression level of …

Male germ cells require multiple epigenetic reprogramming events during their lifespan to
achieve reproductive capacity. An emerging body of compelling data demonstrates that …

Background Conflicting results regarding alterations to sperm DNA methylation in cases of
spermatogenesis defects, male infertility and poor developmental outcomes have been …

Offspring of persons exposed to childhood abuse are at higher risk of neurodevelopmental
and physical health disparities across the life course. Animal experiments have indicated …

During mammalian spermatogenesis, germ cell chromatin undergoes dramatic histone
acetylation-mediated reorganization, whereby 90%–99% of histones are evicted. Given the …

Protamines are nuclear proteins which are specifically expressed in haploid male germ
cells. Their replacement of histones and binding to DNA is followed by chromatin …