Countless times each day, the acute inflammatory response protects us from invading
microbes, injuries, and insults from within, as in surgery-induced tissue injury. These …

The study of the gut microbiome has increasingly revealed an important role in modulating
brain function and mental health. In this review, we underscore specific pathways and …

Practitioners of ancient societies from the time of Hippocrates and earlier recognized and
treated the signs of inflammation, heat, redness, swelling, and pain with agents that block or …

The recent outbreak of infections and the pandemic caused by SARS-CoV-2 represent one
of the most severe threats to human health in more than a century. Emerging data from the …

Abstract The 2019 coronavirus disease (COVID-19) pandemic caused by the virus severe
acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has created an unprecedented …

The acute inflammatory response is host-protective to contain foreign invaders. Many of
today's pharmacopeia that block pro-inflammatory chemical mediators can cause serious …

Although inflammation has a physiological role, unrestrained inflammation can be
detrimental, causing tissue damage and disease. Under normal circumstances inflammation …

While protective, the acute inflammatory response when uncontrolled can lead to further
tissue damage and chronic inflammation that is now widely recognized to play important …

Inflammation not only plays a crucial role in acute ischemic cardiac injury, but also
contributes to post-infarction repair and remodeling. Traditionally, neutrophils have been …

Cardiovascular disease (CVD) is the leading cause of mortality globally. In the past several
decades, researchers have raised significant awareness about the sex differences in CVD …