Zebrafish cancer: the state of the art and the path forward
The zebrafish is a recent addition to animal models of human cancer, and studies using this
model are rapidly contributing major insights. Zebrafish develop cancer spontaneously, after …
model are rapidly contributing major insights. Zebrafish develop cancer spontaneously, after …
Lamarck rises from his grave: parental environment‐induced epigenetic inheritance in model organisms and humans
Y Wang, H Liu, Z Sun - Biological Reviews, 2017 - Wiley Online Library
Organisms can change their physiological/behavioural traits to adapt and survive in
changed environments. However, whether these acquired traits can be inherited across …
changed environments. However, whether these acquired traits can be inherited across …
Reprogramming the maternal zebrafish genome after fertilization to match the paternal methylation pattern
ME Potok, DA Nix, TJ Parnell, BR Cairns - Cell, 2013 - cell.com
Early vertebrate embryos must achieve totipotency and prepare for zygotic genome
activation (ZGA). To understand this process, we determined the DNA methylation (DNAme) …
activation (ZGA). To understand this process, we determined the DNA methylation (DNAme) …
Environmental epigenetics in zebrafish
V Cavalieri, G Spinelli - Epigenetics & chromatin, 2017 - Springer
It is widely accepted that the epigenome can act as the link between environmental cues,
both external and internal, to the organism and phenotype by converting the environmental …
both external and internal, to the organism and phenotype by converting the environmental …
Zebrafish as a model to study the role of DNA methylation in environmental toxicology
Environmental epigenetics is a rapidly growing field which studies the effects of
environmental factors such as nutrition, stress, and exposure to compounds on epigenetic …
environmental factors such as nutrition, stress, and exposure to compounds on epigenetic …
Global and gene specific DNA methylation changes during zebrafish development
X Fang, J Corrales, C Thornton, BE Scheffler… - … and Physiology Part B …, 2013 - Elsevier
DNA methylation is dynamic through the life of an organism. Previous studies have primarily
focused on DNA methylation changes during very early embryogenesis. In this study, global …
focused on DNA methylation changes during very early embryogenesis. In this study, global …
Treatment with a DNA methyltransferase inhibitor feminizes zebrafish and induces long-term expression changes in the gonads
Background The role of epigenetic modifications such as DNA methylation during vertebrate
sexual development is far from being clear. Using the zebrafish model, we tested the effects …
sexual development is far from being clear. Using the zebrafish model, we tested the effects …
Role of epigenetics in zebrafish development
S Balasubramanian, A Raghunath, E Perumal - Gene, 2019 - Elsevier
The role of epigenetics in development has garnered attention in recent years due to their
ability to modulate the embryonic developmental gene expression in response to the …
ability to modulate the embryonic developmental gene expression in response to the …
Mapping the zebrafish brain methylome using reduced representation bisulfite sequencing
A Chatterjee, Y Ozaki, PA Stockwell, JA Horsfield… - Epigenetics, 2013 - Taylor & Francis
Reduced representation bisulfite sequencing (RRBS) has been used to profile DNA
methylation patterns in mammalian genomes such as human, mouse and rat. The …
methylation patterns in mammalian genomes such as human, mouse and rat. The …
Developmental features of DNA methylation during activation of the embryonic zebrafish genome
Background Zygotic genome activation (ZGA) occurs at the mid-blastula transition (MBT) in
zebrafish and is a period of extensive chromatin remodeling. Genome-scale gametic …
zebrafish and is a period of extensive chromatin remodeling. Genome-scale gametic …