[HTML][HTML] Remdesivir for the treatment of COVID‐19

F Grundeis, K Ansems, K Dahms… - … of systematic reviews, 2023 - ncbi.nlm.nih.gov
Background Remdesivir is an antiviral medicine approved for the treatment of mild‐to‐
moderate coronavirus disease 2019 (COVID‐19). This led to widespread implementation …

[HTML][HTML] Post-COVID cognitive dysfunction: current status and research recommendations for high risk population

M Quan, X Wang, M Gong, Q Wang, Y Li… - The Lancet Regional …, 2023 - thelancet.com
Post-COVID cognitive dysfunction (PCCD) is a condition in which patients with a history of
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, usually three …

[HTML][HTML] Chloroquine and hydroxychloroquine toxicity

TJ Stokkermans, DM Falkowitz, G Trichonas - StatPearls [Internet], 2024 - ncbi.nlm.nih.gov
Objectives: Identify the treatment indications for chloroquine and hydroxychloroquine.
Determine the mechanisms of action of chloroquine and hydroxychloroquine. Identify the …

In silico identification of novel benzophenone–coumarin derivatives as SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) inhibitors

SM Patil, RM Martiz, R Ramu, PS Shirahatti… - Journal of …, 2022 - Taylor & Francis
In this study, we propose our novel benzophenone–coumarin derivatives (BCDs) as potent
inhibitors of the RNA-dependent RNA polymerase (RdRp) of SARS-CoV-2 virus, one of the …

[HTML][HTML] Molnupiravir and nirmatrelvir/ritonavir: tolerability, safety, and adherence in a retrospective cohort study

M Mazzitelli, D Mengato, L Sasset, A Ferrari, S Gardin… - Viruses, 2023 - mdpi.com
Background. Molnupiravir (MOL) and nirmatrelvir/ritonavir (NIR) were recently approved for
the early treatment of COVID-19, but real-life data on tolerability, safety, and adverse events …

Remdesivir for the treatment of COVID‐19

Cochrane Haematology Group… - Cochrane Database …, 1996 - cochranelibrary.com
Background Remdesivir is an antiviral medicine approved for the treatment of mild‐to‐
moderate coronavirus disease 2019 (COVID‐19). This led to widespread implementation …

[HTML][HTML] Drug repositioning in the COVID-19 pandemic: fundamentals, synthetic routes, and overview of clinical studies

ES Vaz, SV Vassiliades, J Giarolla, MC Polli… - European Journal of …, 2023 - Springer
Introduction Drug repositioning is a strategy to identify a new therapeutic indication for
molecules that have been approved for other conditions, aiming to speed up the traditional …

[HTML][HTML] Musculoskeletal involvement: COVID-19 and post COVID 19

D Evcik - Turkish Journal of Physical Medicine and …, 2023 - ncbi.nlm.nih.gov
The worldwide pandemic of coronavirus disease 2019 (COVID-19) was known to
predominantly affect the lungs, but it was realized that COVID-19 had a large variety of …

The allergic rhinitis and its impact on asthma (ARIA) approach of value-added medicines: As-needed treatment in allergic rhinitis

J Bousquet, M Toumi, B Sousa-Pinto, JM Anto… - The Journal of Allergy …, 2022 - Elsevier
Drug repurposing is a major field of value-added medicine. It involves investigating and
evaluating existing drugs for new therapeutic purposes that address unmet healthcare …

[HTML][HTML] S protein, ACE2 and host cell proteases in SARS-CoV-2 cell entry and infectivity; is soluble ACE2 a two blade sword? A narrative review

R Nejat, MF Torshizi, DJ Najafi - Vaccines, 2023 - mdpi.com
Since the spread of the deadly virus SARS-CoV-2 in late 2019, researchers have restlessly
sought to unravel how the virus enters the host cells. Some proteins on each side of the …