The review covers various aspects of fluorinated cycloalkyl (C3− C7) building blocks for drug
discovery, including their synthesis, key physicochemical properties, and biological and …

The nickel-catalyzed multicomponent dicarbofunctionalization of alkenes represents one of
the most straightforward approaches to complex organofluorine compounds. However, the …

The radical 1, 2-difunctionalization reaction of alkynes has evolved into a versatile approach
to multisubstituted alkylenes. However, robust catalytic strategies to perform carboamination …

Direct synthesis of gem‐difluorinated carbocyclic molecules represents a longstanding
challenge in organic chemistry. Herein, a Rh‐catalyzed [3+ 2] cycloaddition reaction …

Four Cu (I) bis (phenanthroline) photosensitizers formulated from a new ligand structural
motif (Cu1–Cu4) coded according to their 2, 9-substituents were synthesized, structurally …

The site‐selective introduction of the difluoromethylene group into organic molecules has
important applications in producing pharmaceuticals and agrochemicals. However, the …

The incorporation of the gem‐difluoromethylene (CF2) group into organic frameworks is
highly sought due to the influence of this unit on the physicochemical and pharmacological …

Modern organic chemistry is a titan supporting and reinforcing pharmaceutical, agricultural,
food and material science products. Over the past decades, the organic compounds market …

A nickel-catalyzed reductive cross-coupling of cyclopropylamine NHP esters with (hetero)
aryl halides is reported. This efficient protocol provides direct access to 1 …

Herein we present our studies on the solvent-controlled difunctionalization of alkenes
utilizing chlorodifluoroacetic acid (CDFA) and α-halo carboxylic acids for the synthesis of γ …