[HTML][HTML] Androgen Receptor–Interacting Proteins in Prostate Cancer Development and Therapy Resistance
Endocrine therapy for prostate cancer is based on the use of drugs that diminish androgen
concentration and androgen receptor (AR) signaling inhibitors and is limited by the …
concentration and androgen receptor (AR) signaling inhibitors and is limited by the …
Preclinical models in prostate cancer: Resistance to AR targeting therapies in prostate cancer
Simple Summary In this review, we will look into the existing methods to study treatment
resistance to androgen receptor targeted therapies in prostate cancer. This will encompass …
resistance to androgen receptor targeted therapies in prostate cancer. This will encompass …
[HTML][HTML] High expression of miR-105-1 positively correlates with clinical prognosis of hepatocellular carcinoma by targeting oncogene NCOA1
YS Ma, TM Wu, ZW Lv, GX Lu, XL Cong, RT Xie… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Increasing evidence supports that microRNA (miRNA) plays a significant functional role in
cancer progression by directly regulating respective targets. In this study, the expression …
cancer progression by directly regulating respective targets. In this study, the expression …
The multifaceted therapeutic value of targeting steroid receptor coactivator-1 in tumorigenesis
Abstract Steroid receptor coactivator-1 (SRC-1, also known as NCOA1) frequently functions
as a transcriptional coactivator by directly binding to transcription factors and recruiting to the …
as a transcriptional coactivator by directly binding to transcription factors and recruiting to the …
In silico investigation of the role of miRNAs in a possible developmental origin of prostate cancer in F1 and F2 offspring of mothers exposed to a phthalate mixture
AM Aquino, MN Fioretto… - Environmental …, 2024 - Wiley Online Library
A previous study using miRNA sequencing revealed that exposure to a mixture of phthalates
during pregnancy and lactation dysregulated rno‐miR‐184 and rno‐miR‐141‐3p in the …
during pregnancy and lactation dysregulated rno‐miR‐184 and rno‐miR‐141‐3p in the …
High expression of ladinin-1 (LAD1) predicts adverse outcomes: a new candidate docetaxel resistance gene for prostatic cancer (PCa)
J Li, Z Wang, C Tie - Bioengineered, 2021 - Taylor & Francis
Docetaxel resistance is one of the major obstacles that undermine the treatment outcome of
PCa. Exploring molecular mechanisms associated with docetaxel resistance could provide …
PCa. Exploring molecular mechanisms associated with docetaxel resistance could provide …
The oncogenic roles of nuclear receptor coactivator 1 in human esophageal carcinoma
L Wang, W Li, K Li, Y Guo, D Liu, Z Yao, X Lin… - Cancer …, 2018 - Wiley Online Library
Abstract Nuclear receptor coactivator 1 (NCOA1) plays crucial roles in the regulation of gene
expression mediated by a wide spectrum of steroid receptors such as androgen receptor …
expression mediated by a wide spectrum of steroid receptors such as androgen receptor …
MicroRNA-223-3p inhibits human bladder cancer cell migration and invasion
J Guo, R Cao, X Yu, Z Xiao, Z Chen - Tumor Biology, 2017 - journals.sagepub.com
The regulation of initiation and progression during carcinogenesis of bladder carcinoma is
not completely elucidated. Dysregulation of microRNAs has been detected to play critical …
not completely elucidated. Dysregulation of microRNAs has been detected to play critical …
AR-dependent phosphorylation and phospho-proteome targets in prostate cancer
VB Venkadakrishnan, S Ben-Salem… - Endocrine-related …, 2020 - erc.bioscientifica.com
Prostate cancer (CaP) is the second leading cause of cancer-related deaths in western men.
Because androgens drive CaP by activating the androgen receptor (AR), blocking AR's …
Because androgens drive CaP by activating the androgen receptor (AR), blocking AR's …
Non‐coding and coding genomic variants distinguish prostate cancer, castration‐resistant prostate cancer, familial prostate cancer, and metastatic castration‐resistant …
IO Alanazi, ZS Al Shehri, E Ebrahimie… - Molecular …, 2019 - Wiley Online Library
A considerable number of deposited variants has provided new possibilities for knowledge
discovery in different types of prostate cancer. Here, we analyzed variants located on 3 …
discovery in different types of prostate cancer. Here, we analyzed variants located on 3 …