Tumor cell invasion in glioblastoma
A Vollmann-Zwerenz, V Leidgens, G Feliciello… - International journal of …, 2020 - mdpi.com
Glioblastoma (GBM) is a particularly devastating tumor with a median survival of about 16
months. Recent research has revealed novel insights into the outstanding heterogeneity of …
months. Recent research has revealed novel insights into the outstanding heterogeneity of …
Glioblastoma stem cells: lessons from the tumor hierarchy in a lethal cancer
Glioblastoma ranks among the most lethal of all human cancers. Glioblastomas display
striking cellular heterogeneity, with stem-like glioblastoma stem cells (GSCs) at the apex …
striking cellular heterogeneity, with stem-like glioblastoma stem cells (GSCs) at the apex …
Fatty acid oxidation fuels glioblastoma radioresistance with CD47-mediated immune evasion
N Jiang, B Xie, W Xiao, M Fan, S Xu, Y Duan… - Nature …, 2022 - nature.com
Glioblastoma multiforme (GBM) remains the top challenge to radiotherapy with only 25%
one-year survival after diagnosis. Here, we reveal that co-enhancement of mitochondrial …
one-year survival after diagnosis. Here, we reveal that co-enhancement of mitochondrial …
[HTML][HTML] Outer radial glia-like cancer stem cells contribute to heterogeneity of glioblastoma
Glioblastoma is a devastating form of brain cancer. To identify aspects of tumor
heterogeneity that may illuminate drivers of tumor invasion, we created a glioblastoma tumor …
heterogeneity that may illuminate drivers of tumor invasion, we created a glioblastoma tumor …
[HTML][HTML] Fatty acids and evolving roles of their proteins in neurological, cardiovascular disorders and cancers
The dysregulation of fat metabolism is involved in various disorders, including
neurodegenerative, cardiovascular, and cancers. The uptake of long-chain fatty acids …
neurodegenerative, cardiovascular, and cancers. The uptake of long-chain fatty acids …
Personalized immunotherapy against several neuronal and brain tumors
S Kuttruff-coqui, T Weinschenk, J Fritsche… - US Patent …, 2021 - Google Patents
2014-11-12 Assigned to IMMATICS BIOTECHNOLOGIES GMBH reassignment IMMATICS
BIOTECHNOLOGIES GMBH ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …
BIOTECHNOLOGIES GMBH ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …
Metabolic abnormalities in glioblastoma and metabolic strategies to overcome treatment resistance
W Zhou, DR Wahl - Cancers, 2019 - mdpi.com
Glioblastoma (GBM) is the most common and aggressive primary brain tumor and is nearly
universally fatal. Targeted therapy and immunotherapy have had limited success in GBM …
universally fatal. Targeted therapy and immunotherapy have had limited success in GBM …
Infiltrative and drug‐resistant slow‐cycling cells support metabolic heterogeneity in glioblastoma
LB Hoang‐Minh, FA Siebzehnrubl, C Yang… - The EMBO …, 2018 - embopress.org
Metabolic reprogramming has been described in rapidly growing tumors, which are thought
to mostly contain fast‐cycling cells (FCC s) that have impaired mitochondrial function and …
to mostly contain fast‐cycling cells (FCC s) that have impaired mitochondrial function and …
Fatty acid signaling mechanisms in neural cells: fatty acid receptors
LJ Falomir-Lockhart, GF Cavazzutti… - Frontiers in cellular …, 2019 - frontiersin.org
Fatty acids (FAs) are typically associated with structural and metabolic roles, as they can be
stored as triglycerides, degraded by β-oxidation or used in phospholipids' synthesis, the …
stored as triglycerides, degraded by β-oxidation or used in phospholipids' synthesis, the …
Maternal supply of both arachidonic and docosahexaenoic acids is required for optimal neurodevelopment
During the last trimester of gestation and for the first 18 months after birth, both
docosahexaenoic acid, 22: 6n-3 (DHA) and arachidonic acid, 20: 4n-6 (ARA) are …
docosahexaenoic acid, 22: 6n-3 (DHA) and arachidonic acid, 20: 4n-6 (ARA) are …