Cognitive impairment after cancer treatment: mechanisms, clinical characterization, and management
B Fleming, P Edison, L Kenny - bmj, 2023 - bmj.com
Cognitive impairment is a debilitating side effect experienced by patients with cancer treated
with systemically administered anticancer therapies. With around 19.3 million new cases of …
with systemically administered anticancer therapies. With around 19.3 million new cases of …
A review on the neurotoxic effects of doxorubicin
K Kamińska, A Cudnoch-Jędrzejewska - Neurotoxicity Research, 2023 - Springer
Anthracyclines, a class of drugs considered as most effective anticancer drugs, used in the
various regimens of cancer chemotherapy, induce long-term impairment of mitochondrial …
various regimens of cancer chemotherapy, induce long-term impairment of mitochondrial …
Statins and left ventricular ejection fraction following doxorubicin treatment
WG Hundley, R D'Agostino, T Crotts, K Craver… - NEJM …, 2022 - evidence.nejm.org
Background Statins taken for cardiovascular indications by patients with breast cancer and
lymphoma during doxorubicin treatment may attenuate left ventricular ejection fraction …
lymphoma during doxorubicin treatment may attenuate left ventricular ejection fraction …
Nose-to-brain delivery of chrysin transfersomal and composite vesicles in doxorubicin-induced cognitive impairment in rats: Insights on formulation, oxidative stress …
SS Ibrahim, OGA Elseoud, MH Mohamedy, MM Amer… - …, 2021 - Elsevier
Many cancer survivors suffer from chemotherapy-induced cognitive impairment known as
'Chemobrain'. Doxorubicin-topoisomerase II inhibitor-is widely used in breast cancer …
'Chemobrain'. Doxorubicin-topoisomerase II inhibitor-is widely used in breast cancer …
[HTML][HTML] Comparative evaluation of doxorubicin, cyclophosphamide, 5-fluorouracil, and cisplatin on cognitive dysfunction in rats: Delineating the role of inflammation of …
LI Alotayk, MA Aldubayan, SK Alenezi… - Biomedicine & …, 2023 - Elsevier
Chemotherapeutic agents such as doxorubicin, cyclophosphamide, fluorouracil, and
cisplatin are commonly used to treat a variety of cancers and often result in chemobrain …
cisplatin are commonly used to treat a variety of cancers and often result in chemobrain …
Artificial and natural interventions for chemotherapy-and/or radiotherapy-induced cognitive impairment: A systematic review of animal studies
LE Kuil, T Varkevisser, MH Huisman, M Jansen… - Neuroscience & …, 2023 - Elsevier
Background Cancer survivors frequently experience cognitive impairments. This systematic
review assessed animal literature to identify artificial (pharmaceutical) or natural …
review assessed animal literature to identify artificial (pharmaceutical) or natural …
Four decades of chemotherapy-induced cognitive dysfunction: Comprehensive review of clinical, animal and in vitro studies, and insights of key initiating events
A Dias-Carvalho, M Ferreira, R Ferreira, ML Bastos… - Archives of …, 2022 - Springer
Cognitive dysfunction has been one of the most reported and studied adverse effects of
cancer treatment, but, for many years, it was overlooked by the medical community …
cancer treatment, but, for many years, it was overlooked by the medical community …
Infliximab and/or MESNA alleviate doxorubicin-induced Alzheimer's disease-like pathology in rats: A new insight into TNF-α/Wnt/β-catenin signaling pathway
HE Mohamad, DM Abo-Elmatty, NS Wahba… - Life Sciences, 2022 - Elsevier
Aims The current study aimed to elucidate the neurotoxic potential of DOX to induce AD-like
pathology paying attention to the role of wingless-integrated/β-catenin (Wnt/β-catenin) …
pathology paying attention to the role of wingless-integrated/β-catenin (Wnt/β-catenin) …
Neuropathological effects of chemotherapeutic drugs
A Umfress, HE Speed, C Tan, S Ramezani… - ACS chemical …, 2021 - ACS Publications
Novel treatments, screening, and detection methods have prolonged the lives of numerous
cancer patients worldwide. Unfortunately, existing and many promising new …
cancer patients worldwide. Unfortunately, existing and many promising new …
[PDF][PDF] Recent progress in the elucidation of the mechanisms of chemotherapy-induced cognitive impairment.
AH Alhowail, M Aldubayan - European Review for Medical & …, 2021 - europeanreview.org
The term “chemobrain” refers to the cognitive dysfunction that occurs after chemotherapy,
and it is also known as chemotherapy-induced cognitive impairment or “chemofog”. The aim …
and it is also known as chemotherapy-induced cognitive impairment or “chemofog”. The aim …