The transmission of dengue virus (DENV) from an infected Aedes mosquito to a human,
causes illness ranging from mild dengue fever to fatal dengue shock syndrome. The similar …

Zika virus (ZIKV) had remained a relatively obscure flavivirus until a recent series of
outbreaks accompanied by unexpectedly severe clinical complications brought this virus …

Currently circulating SARS-CoV-2 variants have acquired convergent mutations at hot spots
in the receptor-binding domain (RBD) of the spike protein. The effects of these mutations on …

Arthritogenic alphaviruses comprise a group of enveloped RNA viruses that are transmitted
to humans by mosquitoes and cause debilitating acute and chronic musculoskeletal …

Zika virus (ZIKV), a mosquito-borne flavivirus, is a current global public health concern. The
flavivirus envelope (E) glycoprotein is responsible for virus entry and represents a major …

Zika virus (ZIKV) is an emerging mosquito-transmitted flavivirus that can cause severe
disease, including congenital birth defects during pregnancy 1. To develop candidate …

Zika virus (ZIKV) infection during pregnancy has emerged as a global public health problem
because of its ability to cause severe congenital disease. Here, we developed six mouse …

Dengue virus poses a major threat to global public health: two-thirds of the world's
population is now at risk from infection by this mosquito-borne virus. Dengue virus causes a …

Progress toward understanding Zika virus (ZIKV) pathogenesis is hindered by lack of
immunocompetent small animal models, in part because ZIKV fails to effectively antagonize …

A fascinating aspect of viral evolution relates to the ability of viruses to escape the adaptive
immune response. The widely held view has been that the great variability of viral …