o-Silylaryl Triflates: A Journey of Kobayashi Aryne Precursors
J Shi, L Li, Y Li - Chemical Reviews, 2021 - ACS Publications
Arynes are among the most active organic intermediates and have found numerous
applications in expeditious preparation of substituted arenes. In the past 20 years, chemists …
applications in expeditious preparation of substituted arenes. In the past 20 years, chemists …
Recent advances in transition-metal-free carbon–carbon and carbon–heteroatom bond-forming reactions using arynes
This tutorial review is aimed at highlighting recent developments in transition-metal-free
carbon–carbon and carbon–heteroatom bond-forming reactions utilizing a versatile class of …
carbon–carbon and carbon–heteroatom bond-forming reactions utilizing a versatile class of …
Use of benzynes for the synthesis of heterocycles
AV Dubrovskiy, NA Markina, RC Larock - Organic & Biomolecular …, 2013 - pubs.rsc.org
About two decades after Kobayashi's discovery in 1983 of a very mild way of generating
highly reactive aryne intermediates, the synthetic community embraced o-(trimethylsilyl) aryl …
highly reactive aryne intermediates, the synthetic community embraced o-(trimethylsilyl) aryl …
Pyridynes and indolynes as building blocks for functionalized heterocycles and natural products
Heterocyclic arynes, or hetarynes, have been studied for over 100 years. However,
challenges associated with observing these reactive species, as well as developing …
challenges associated with observing these reactive species, as well as developing …
Regioselective reactions of 3, 4-pyridynes enabled by the aryne distortion model
The pyridine heterocycle continues to play a vital role in the development of human
medicines. More than 100 currently marketed drugs contain this privileged unit, which …
medicines. More than 100 currently marketed drugs contain this privileged unit, which …
The direct acyl-alkylation of arynes
The Direct Acyl-Alkylation of Arynes | Journal of the American Chemical Society ACS ACS
Publications C&EN CAS Find my institution Log In Journal of the American Chemical Society …
Publications C&EN CAS Find my institution Log In Journal of the American Chemical Society …
Recent applications of aryne chemistry to organic synthesis. A review
R Sanz - Organic Preparations and Procedures International, 2008 - Taylor & Francis
Arynes are neutral intermediates in which two adjacent atoms of an aromatic ring lack
substituents, thus leaving two atomic orbitals (perpendicular to the aromatic x system) to …
substituents, thus leaving two atomic orbitals (perpendicular to the aromatic x system) to …
Facile N-Arylation of Amines and Sulfonamides and O-Arylation of Phenols and Arenecarboxylic Acids
Z Liu, RC Larock - The Journal of organic chemistry, 2006 - ACS Publications
An efficient, transition-metal-free procedure for the N-arylation of amines, sulfonamides, and
carbamates and O-arylation of phenols and carboxylic acids has been achieved by allowing …
carbamates and O-arylation of phenols and carboxylic acids has been achieved by allowing …
Efficient synthesis of ureas by direct palladium-catalyzed oxidative carbonylation of amines
B Gabriele, G Salerno, R Mancuso… - The Journal of organic …, 2004 - ACS Publications
A general synthesis of symmetrically disubstituted ureas and trisubstituted ureas by direct Pd-
catalyzed oxidative carbonylation of primary amines or of a mixture of a primary and a …
catalyzed oxidative carbonylation of primary amines or of a mixture of a primary and a …
CO2 Incorporation Reaction Using Arynes: Straightforward Access to Benzoxazinone
CO2 Incorporation Reaction Using Arynes: Straightforward Access to Benzoxazinone |
Journal of the American Chemical Society ACS ACS Publications C&EN CAS Find my …
Journal of the American Chemical Society ACS ACS Publications C&EN CAS Find my …