Low-field nuclear magnetic resonance (NMR) has three general modalities: spectroscopy,
imaging, and relaxometry. In the last twelve years, the modality of spectroscopy, also known …

The pharmaceutical industry is now paying increased attention to continuous manufacturing.
While the revolution to continuous and automated manufacturing is deepening in most of the …

As organic chemistry becomes an increasingly data-rich field, there is a need for methods to
rapidly build and parameterize models for further development. We demonstrate the …

This review reports on an overview of key enablers of acceleration/pandemic and
preparedness, covering CMC strategies as well as technical innovations in vaccine …

The pharmaceutical industry has traditionally employed batch processing as a means of
synthesizing active pharmaceutical ingredients (APIs) on a commercial scale. Batch …

Belzutifan has been approved recently by the US Food and Drug Administration (FDA) for
treating patients with certain types of Von Hippel-Lindau (VHL) disease-associated tumors …

The real-time, in-line monitoring of continuous flow concentrations is widely conducted via
infrared (IR) spectrometry by using a flow cell connected to a reactive flow stream. For …

A scalable continuous manufacturing process for the synthesis and crystallization of form III
carbamazepine (CBZ) from iminostilbene (ISB) has been established. A high-yielding …

A methodical development approach was deployed in a novel portable manufacturing
(Pharmacy on Demand) unit to purify ciprofloxacin hydrochloride hydrate within assay, water …

This is Part II of a series on the development and characterization of an integrated
continuous manufacturing (CM) process developed for the penultimate step in the synthesis …