Cellular senescence is a major contributor to age-related diseases in humans; however, it
also has a beneficial role in physiological and pathological processes, including wound …

Senile osteoporosis has become a worldwide bone disease with the aging of the world
population. It increases the risk of bone fracture and seriously affects human health. Unlike …

Senile osteoporosis (SOP) is widely regarded as one of the typical aging-related diseases
due to a decrease in bone mass and the destruction in microarchitecture. The inhibition of …

Bioprinting is a promising technique for facilitating the fabrication of engineered bone
tissues for patient-specific defect repair and for developing in vitro tissue/organ models for …

Senescence of bone marrow-derived mesenchymal stem cells (BMSCs) has been widely
reported to be closely correlated with aging-related diseases, including osteoporosis (OP) …

Blood production depends on rare haematopoietic stem cells (HSCs) and haematopoietic
stem and progenitor cells (HSPCs) that ultimately take up residence in the bone marrow …

Over the past decades, mesenchymal stem cell (MSC)-based therapy has been intensively
investigated and shown promising results in the treatment of various diseases due to their …

Tremendous advances in tissue engineering and regenerative medicine have revealed the
potential of fabricating biomaterials to solve the dilemma of bone and articular defects by …

Simple Summary Aging and frailty are complex processes implicating multifactorial
mechanisms, which demand for new therapeutic strategies against their devastating effects …

Advances in bioprinting have enabled the fabrication of complex tissue constructs with high
speed and resolution. However, there remains significant structural and biological …