The biology, function, and biomedical applications of exosomes
BACKGROUND All cells, prokaryotes and eukaryotes, release extracellular vesicles (EVs)
as part of their normal physiology and during acquired abnormalities. EVs can be broadly …
as part of their normal physiology and during acquired abnormalities. EVs can be broadly …
Circulating biomarkers in patients with glioblastoma
J Müller Bark, A Kulasinghe, B Chua, BW Day… - British journal of …, 2020 - nature.com
Gliomas are the most common tumours of the central nervous system and the most
aggressive form is glioblastoma (GBM). Despite advances in treatment, patient survival …
aggressive form is glioblastoma (GBM). Despite advances in treatment, patient survival …
Exosome: a significant nano-scale drug delivery carrier
H Peng, W Ji, R Zhao, J Yang, Z Lu, Y Li… - Journal of Materials …, 2020 - pubs.rsc.org
In recent years, due to the limitations of the nature of therapeutic agents, many synthetic
nano-delivery systems have emerged to enhance the efficacy of drugs. Extracellular vesicles …
nano-delivery systems have emerged to enhance the efficacy of drugs. Extracellular vesicles …
A review on artificial intelligence and machine learning to improve cancer management and drug discovery
Typical pharmacological effect screening techniques use diluted natural ingredients that do
not segregate active components. For the last two decades, contemporary medicine has …
not segregate active components. For the last two decades, contemporary medicine has …
[HTML][HTML] Exosomes and extracellular vesicles: Rethinking the essential values in cancer biology
A Yokoi, T Ochiya - Seminars in cancer biology, 2021 - Elsevier
Extracellular vesicles (EVs) such as exosomes are released by all living cells and contain
diverse bioactive molecules, including nucleic acids, proteins, lipids, and metabolites …
diverse bioactive molecules, including nucleic acids, proteins, lipids, and metabolites …
Liquid biopsy in gliomas: A RANO review and proposals for clinical applications
R Soffietti, C Bettegowda, IK Mellinghoff… - Neuro …, 2022 - academic.oup.com
Background There is an extensive literature highlighting the utility of blood-based liquid
biopsies in several extracranial tumors for diagnosis and monitoring. Methods The RANO …
biopsies in several extracranial tumors for diagnosis and monitoring. Methods The RANO …
Serum extracellular vesicle-derived circHIPK3 and circSMARCA5 are two novel diagnostic biomarkers for glioblastoma multiforme
Glioblastoma multiforme (GBM) is the most frequent and deadly human brain cancer. Early
diagnosis through non-invasive biomarkers may render GBM more easily treatable …
diagnosis through non-invasive biomarkers may render GBM more easily treatable …
Hatching is modulated by microRNA-378a-3p derived from extracellular vesicles secreted by blastocysts
KC Pavani, T Meese, OB Pascottini… - Proceedings of the …, 2022 - National Acad Sciences
Extracellular vesicles (EVs) and their cargo microRNAs (miRNAs) are important regulators of
embryo development to the blastocyst stage and beyond. Before implantation can take …
embryo development to the blastocyst stage and beyond. Before implantation can take …
Genome-wide methylation profiling of glioblastoma cell-derived extracellular vesicle DNA allows tumor classification
CL Maire, MM Fuh, K Kaulich, KD Fita, I Stevic… - Neuro …, 2021 - academic.oup.com
Background Genome-wide DNA methylation profiling has recently been developed into a
tool that allows tumor classification in central nervous system tumors. Extracellular vesicles …
tool that allows tumor classification in central nervous system tumors. Extracellular vesicles …
The role of MiRNA in cancer: pathogenesis, diagnosis, and treatment
Cancer is also determined by the alterations of oncogenes and tumor suppressor genes.
These gene expressions can be regulated by microRNAs (miRNA). At this point, researchers …
These gene expressions can be regulated by microRNAs (miRNA). At this point, researchers …