Excretory–secretory products of helminth parasites: effects on host immune responses

MW Lightowlers, MD Rickard - Parasitology, 1988 - cambridge.org
Parasitic helminths excrete or secrete (ES) a variety of molecules into their mammalian
hosts. The effects of these ES products on the host's immune responses are reviewed …

The secretome of the filarial parasite, Brugia malayi: proteomic profile of adult excretory–secretory products

JP Hewitson, YM Harcus, RS Curwen, AA Dowle… - Molecular and …, 2008 - Elsevier
The secretome of a parasite in its definitive host can be considered to be its genome in trans,
to the extent that secreted products encoded by the parasite fulfill their function in the host …

Specific and cross-reactive antigens of Echinococcus granulosus hydatid cyst fluid

JC Shepherd, DP McManus - Molecular and biochemical parasitology, 1987 - Elsevier
The parasite antigens of Echinococcus granulosus hydatid cyst fluid have been
characterised using the techniques of radioiodination, immunoprecipitation, SDS-PAGE, and …

Phosphorylcholine‐bearing antigens in filarial nematode parasites: analysis of somatic extracts, in‐vitro secretions and infection sera from Brugia malayi and B …

RM Maizels, J Burke, DA Denham - Parasite Immunology, 1987 - Wiley Online Library
A set of cross‐reactive antigens is described which are present in somatic extracts and in‐
vitro secretions of the filarial nematodes Brugia pahangi and B. malayi. A monoclonal …

Molecular characterization of antigens of lymphatic filarial parasites

ME Selkirk, DA Denham, F Partono, I Sutanto… - Parasitology, 1986 - cambridge.org
Three species of filarial worms, Wuchereria bancrofti, Brugia malayi and Brugia timori, are
the causative agents of lymphatic filariasis in man, defined by the characteristic tropism of …

Heligmosomoides polygyrus elicits a dominant nonprotective antibody response directed against restricted glycan and peptide epitopes

JP Hewitson, KJ Filbey, JR Grainger… - The Journal of …, 2011 - journals.aai.org
Heligmosomoides polygyrus is a widely used gastrointestinal helminth model of long-term
chronic infection in mice, which has not been well-characterized at the antigenic level. We …

Identification, synthesis and immunogenicity of cuticular collagens from the filarial nematodes Brugia malayi and Brugia pahangi

ME Selkirk, L Nielsen, C Kelley, F Partono… - Molecular and …, 1989 - Elsevier
The major structural proteins of the cuticle of the filarial nematode parasites Brugia malayi
and Brugia pahangi were identified by extrinsic iodination and sensitivity to clostridial …

Filarial surface antigens: the major 29 kilodalton glycoprotein and a novel 17–200 kilodalton complex from adult Brugia malayi parasites

RM Maizels, WF Gregory, GE Kwan-Lim… - Molecular and …, 1989 - Elsevier
Adult Brugia malayi nematode parasites possess a range of cuticular and epicuticular
molecules which may be defined by various surface-labelling techniques. We present here …

[HTML][HTML] Novel O-linked methylated glycan antigens decorate secreted immunodominant glycoproteins from the intestinal nematode Heligmosomoides polygyrus

JP Hewitson, DL Nguyen, A van Diepen… - International Journal for …, 2016 - Elsevier
Glycan molecules from helminth parasites have been associated with diverse biological
functions ranging from interactions with neighbouring host cell populations to down …

Secreted antigens of filarial nematodes: a survey and characterization of in vitro excreted/secreted products of adult Brugia malayi

GE Kwan–Lim, WF Gregory, ME Selkirk… - Parasite …, 1989 - Wiley Online Library
We report here a broad analysis of the excretory/secretory (E/S) products of adult Brugia
malayi, collected by in–vitro cultivation of the parasite. Culture media and conditions were …