Neural regeneration and the peripheral olfactory system

JE Schwob - The Anatomical Record: An Official Publication of …, 2002 - Wiley Online Library
The peripheral olfactory system is able to recover after injury, ie, the olfactory epithelium
reconstitutes, the olfactory nerve regenerates, and the olfactory bulb is reinnervated, with a …

Axonal wiring in the mouse olfactory system

P Mombaerts - Annu. Rev. Cell Dev. Biol., 2006 - annualreviews.org
The main olfactory epithelium of the mouse is a mosaic of 2000 populations of olfactory
sensory neurons (OSNs). Each population expresses one allele of one of the 1000 intact …

Endothelial NT-3 delivered by vasculature and CSF promotes quiescence of subependymal neural stem cells through nitric oxide induction

AC Delgado, SR Ferron, D Vicente, E Porlan… - Neuron, 2014 - cell.com
Interactions of adult neural stem cells (NSCs) with supportive vasculature appear critical for
their maintenance and function, although the molecular details are still under investigation …

BDNF control of adult SVZ neurogenesis

KG Bath, MR Akins, FS Lee - Developmental psychobiology, 2012 - Wiley Online Library
The sensory processing of odorants is a dynamic process that requires plasticity at multiple
levels. In the olfactory bulb (OB), inhibitory interneurons undergo lifelong replacement …

Variant brain-derived neurotrophic factor (Val66Met) alters adult olfactory bulb neurogenesis and spontaneous olfactory discrimination

KG Bath, N Mandairon, D Jing… - Journal of …, 2008 - Soc Neuroscience
Neurogenesis, the division, migration, and differentiation of new neurons, occurs throughout
life. Brain derived neurotrophic factor (BDNF) has been identified as a potential signaling …

How smell develops

P Mombaerts - nature neuroscience, 2001 - nature.com
The mouse's sense of smell is built of∼ 1000 input channels. Each of these consists of a
population of olfactory sensory neurons that express the same odorant receptor gene and …

Neurotrophic factor control of adult SVZ neurogenesis

KG Bath, FS Lee - Developmental neurobiology, 2010 - Wiley Online Library
Neurogenesis is the process by which cells divide, migrate, and subsequently differentiate
into a neuronal phenotype. Significant rates of neurogenesis persist into adulthood in two …

Genetic modulation of BDNF signaling affects the outcome of axonal competition in vivo

L Cao, A Dhilla, J Mukai, R Blazeski, C Lodovichi… - Current Biology, 2007 - cell.com
Background Activity-dependent competition that operates on branch stability or formation
plays a critical role in shaping the pattern and complexity of axonal terminal arbors. In the …

Neurotrophin modulation of voltage‐gated potassium channels in rat through TrkB receptors is time and sensory experience dependent

K Tucker, DA Fadool - The Journal of physiology, 2002 - Wiley Online Library
The whole‐cell configuration of the patch‐clamp technique, immunoprecipitation
experiments and unilateral naris occlusions were used to investigate whether the voltage …

Developing and maintaining a nose-to-brain map of odorant identity

A Dorrego-Rivas, MS Grubb - Open Biology, 2022 - royalsocietypublishing.org
Olfactory sensory neurons (OSNs) in the olfactory epithelium of the nose transduce chemical
odorant stimuli into electrical signals. These signals are then sent to the OSNs' target …