Cerebellar granule cells as a model to study mechanisms of neuronal apoptosis or survivalin vivo andin vitro
A Contestabile - The cerebellum, 2002 - Springer
Granule cells of the cerebellum constitute the largest homogeneous neuronal population of
mammalian brain. Due to their postnatal generation and the feasibility of well characterized …
mammalian brain. Due to their postnatal generation and the feasibility of well characterized …
D-Serine regulates cerebellar LTD and motor coordination through the δ2 glutamate receptor
W Kakegawa, Y Miyoshi, K Hamase, S Matsuda… - Nature …, 2011 - nature.com
Abstract d-Serine (d-Ser) is an endogenous co-agonist for NMDA receptors and regulates
neurotransmission and synaptic plasticity in the forebrain. d-Ser is also found in the …
neurotransmission and synaptic plasticity in the forebrain. d-Ser is also found in the …
Neuronal nitric oxide synthase expression in cerebellar mutant mice
LC Abbott, SS Nahm - The Cerebellum, 2004 - Springer
Nitric oxide (NO) is a diffusible, multifunctional signaling molecule found in many areas of
the brain. NO signaling is involved in a wide array of neurophysiological functions including …
the brain. NO signaling is involved in a wide array of neurophysiological functions including …
Choline acetyltransferase activity at different ages in brain of Ts65Dn mice, an animal model for Down's syndrome and related neurodegenerative diseases
A Contestabile, T Fila, R Bartesaghi… - Journal of …, 2006 - Wiley Online Library
Ts65Dn mice, trisomic for a portion of chromosome 16 segmentally homologous to human
chromosome 21, are an animal model for Down's syndrome and related neurodegenerative …
chromosome 21, are an animal model for Down's syndrome and related neurodegenerative …
Developmental effects of in vivo and in vitro inhibition of nitric oxide synthase in neurons
M Virgili, B Monti, A LoRusso, M Bentivogli… - Brain research, 1999 - Elsevier
The diffusible chemical messenger nitric oxide (NO) is involved in neuronal plasticity and it
is, therefore, supposed to play a role in brain development. A shortage of NO during the …
is, therefore, supposed to play a role in brain development. A shortage of NO during the …
Developmental expression of the cell cycle and apoptosis controlling gene, Lot1, in the rat cerebellum and in cultures of cerebellar granule cells
E Ciani, M Frenquelli, A Contestabile - Developmental brain research, 2003 - Elsevier
The Lot1 gene encodes a zinc finger protein that, in vitro, concurrently regulates apoptosis
and cell cycle arrest and belongs to a recently identified family of proteins with oncogenic …
and cell cycle arrest and belongs to a recently identified family of proteins with oncogenic …
Altered neuronal nitric oxide synthase expression in the cerebellum of calcium channel mutant mice
SS Nahm, SJ Hwang, H Kim, YS Suh, SI Oda, TC Frank… - Brain research, 2003 - Elsevier
Tottering, rolling Nagoya, and leaner mutant mice all exhibit cerebellar ataxia to varying
degrees, from mild (tottering mice) to severe (leaner mice). Collectively, these mice are …
degrees, from mild (tottering mice) to severe (leaner mice). Collectively, these mice are …
Altered nitric oxide synthase and PKC activities in cerebellum of gamma-irradiated neonatal rats
MAZ Zubilete, H Ríos, DM Silberman, LR Guelman… - Brain research, 2005 - Elsevier
In this study, we show that one single dose of gamma-irradiation at birth induces an
inhibition of the cerebellar calcium dependent nitric oxide synthase (NOS) activity, probably …
inhibition of the cerebellar calcium dependent nitric oxide synthase (NOS) activity, probably …
Partial neuroprotection by 17-β-estradiol in neonatal gamma-irradiated rat cerebellum
MAZ Zubilete, LR Guelman, DG Maur… - Neurochemistry …, 2011 - Elsevier
Acute and long-term complications can occur in patients receiving radiation therapy. It has
been suggested that cytoprotection might decrease the incidence and severity of therapy …
been suggested that cytoprotection might decrease the incidence and severity of therapy …
Prenatal low-level exposure to CO alters postnatal development of hippocampal nitric oxide synthase and haem-oxygenase activities in rats
A Vaccari, S Ruiu, P Saba, M Fà… - International Journal …, 2001 - academic.oup.com
The effects of prenatal CO exposure (150 ppm from days 0 to 20 of pregnancy) on the
postnatal development of hippocampal neuronal NO synthase (n NOS) and haem …
postnatal development of hippocampal neuronal NO synthase (n NOS) and haem …