Endothelial cell function in diabetic microangiopathy
M Porta, M La Selva, P Molinatti, GM Molinatti - Diabetologia, 1987 - Springer
Conclusions Endothelial cells are directly exposed to altered concentrations of circulating
metabolites in diabetes and are likely to be involved early, if not primarily, in the natural …
metabolites in diabetes and are likely to be involved early, if not primarily, in the natural …
Specificity, pathogenecity, and clinical value of antiendothelialcell antibodies
C Belizna, JWC Tervaert - Seminars in arthritis and rheumatism, 1997 - Elsevier
OBJECTIVE:: To characterize the putative target antigens for antiendothelial cell antibodies
(AECA), the possible pathophysiological role of AECA, and the clinical value of these …
(AECA), the possible pathophysiological role of AECA, and the clinical value of these …
Hydrogen peroxide stimulates the synthesis of platelet-activating factor by endothelium and induces endothelial cell-dependent neutrophil adhesion.
MS Lewis, RE Whatley, P Cain… - The Journal of …, 1988 - Am Soc Clin Investig
Oxidant-induced damage to the intima of pulmonary and systemic vessels is thought to be
an important mechanism of injury in a variety of syndromes of vascular damage. Hydrogen …
an important mechanism of injury in a variety of syndromes of vascular damage. Hydrogen …
Characterization of serum platelet-activating factor (PAF) acetylhydrolase. Correlation between deficiency of serum PAF acetylhydrolase and respiratory symptoms in …
M Miwa, T Miyake, T Yamanaka… - The Journal of …, 1988 - Am Soc Clin Investig
Platelet-activating factor (PAF) acetylhydrolase has been recognized as an enzyme that
inactivates PAF. We developed a convenient and reproducible method for determining …
inactivates PAF. We developed a convenient and reproducible method for determining …
Platelet-activating factor mediates hemodynamic changes and lung injury in endotoxin-treated rats.
SW Chang, CO Feddersen, PM Henson… - The Journal of …, 1987 - Am Soc Clin Investig
Within 20 min after intraperitoneal injection of Salmonella enteritidis endotoxin in rats, blood
platelet-activating factor (PAF) increased from 4.3+/-1.3 to 13.7+/-2.0 ng/ml (P less than 0.01) …
platelet-activating factor (PAF) increased from 4.3+/-1.3 to 13.7+/-2.0 ng/ml (P less than 0.01) …
Tumor necrosis factor/cachectin stimulates peritoneal macrophages, polymorphonuclear neutrophils, and vascular endothelial cells to synthesize and release platelet …
G Camussi, F Bussolino, G Salvidio… - The Journal of …, 1987 - rupress.org
Murine tumor necrosis factor (mTNF) stimulates production of platelet-activating factor (PAF)
by cultured rat peritoneal macrophages in amounts comparable to those formed during …
by cultured rat peritoneal macrophages in amounts comparable to those formed during …
Interleukin 1 stimulates platelet-activating factor production in cultured human endothelial cells.
Monocyte-derived interleukin 1 (IL-1) was found to be a potent inducer of platelet-activating
factor (PAF) in cultured human vascular endothelial cells (HEC). The product was identified …
factor (PAF) in cultured human vascular endothelial cells (HEC). The product was identified …
Potent ulcerogenic actions of platelet-activating factor on the stomach
AC Rosam, JL Wallace, BJR Whittle - Nature, 1986 - nature.com
Platelet-activating factor (PAF) is an endogenous phospholipid which has been implicated
as a mediator of allergic and inflammatory processes1. It is synthesized and released by …
as a mediator of allergic and inflammatory processes1. It is synthesized and released by …
Multidrug-resistance P-glycoprotein (MDR1) secretes platelet-activating factor
RJ Raggers, I VOGELS, G van MEER - Biochemical Journal, 2001 - portlandpress.com
The human multidrug-resistance (MDR1) P-glycoprotein (Pgp) is an ATP-binding-cassette
transporter (ABCB1) that is ubiquitously expressed. Often its concentration is high in the …
transporter (ABCB1) that is ubiquitously expressed. Often its concentration is high in the …
Platelets mediate neutrophil-dependent immune complex nephritis in the rat.
RJ Johnson, CE Alpers, P Pritzl… - The Journal of …, 1988 - Am Soc Clin Investig
Neutrophils and platelets are frequently present in glomeruli in immune glomerulonephritis
(GN). No role for the platelet in acute neutrophil-mediated renal injury has been defined. We …
(GN). No role for the platelet in acute neutrophil-mediated renal injury has been defined. We …