[HTML][HTML] Model-informed precision dosing: State of the art and future perspectives

IK Minichmayr, E Dreesen, M Centanni, Z Wang… - Advanced drug delivery …, 2024 - Elsevier
Abstract Model-informed precision dosing (MIPD) stands as a significant development in
personalized medicine to tailor drug dosing to individual patient characteristics. MIPD moves …

Practical management of mild-to-moderate ulcerative colitis: an international expert consensus

F D'Amico, F Magro, A Dignass… - Expert Review of …, 2024 - Taylor & Francis
Introduction Although there are well-defined guidelines for the management of mild-to-
moderate ulcerative colitis (UC), there are still unmet needs. For this reason, we conducted …

AGA clinical practice guideline on the management of pouchitis and inflammatory pouch disorders

EL Barnes, M Agrawal, G Syal, AN Ananthakrishnan… - Gastroenterology, 2024 - Elsevier
Background & Aims Pouchitis is the most common complication after restorative
proctocolectomy with ileal pouch–anal anastomosis for ulcerative colitis. This American …

AGA clinical practice guideline on the role of biomarkers for the management of Crohn's disease

AN Ananthakrishnan, J Adler, KA Chachu, NH Nguyen… - Gastroenterology, 2023 - Elsevier
Background & Aims Biomarkers are used frequently for evaluation and monitoring of
patients with Crohn's disease (CD). This American Gastroenterological Association (AGA) …

Microcapsules based on biological macromolecules for intestinal health: A review

M Xu, G Feng, J Fang - International Journal of Biological Macromolecules, 2024 - Elsevier
Intestinal dysfunction is becoming increasingly associated with neurological and endocrine
issues, raising concerns about its impact on world health. With the introduction of several …

Formononetin ameliorates dextran sulfate sodium-induced colitis via enhancing antioxidant capacity, promoting tight junction protein expression and reshaping M1 …

Q Xiao, J Huang, X Zhu, M Shi, L Chen, L Chen… - International …, 2024 - Elsevier
Ulcerative colitis (UC) is a complex, refractory inflammatory bowel disease characterized
impared intestinal mucosal barrier and imbalanced M1/M2 macrophage polarization …

Fecal calprotectin and endoscopic scores: the cornerstones in clinical practice for evaluating mucosal healing in inflammatory bowel disease

MH de Magalhães Costa, LY Sassaki… - World Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Managing inflammatory bowel disease (IBD) is becoming increasingly complex and
personalized, considering the advent of new advanced therapies with distinct mechanisms …

Current approaches for monitoring of patients with inflammatory bowel diseases: a narrative review

A Vitello, M Maida, E Shahini, FS Macaluso… - Journal of Clinical …, 2024 - mdpi.com
Background: Patients with inflammatory bowel diseases (IBD) require proactive monitoring
both during the active phase to evaluate therapeutic response and during the remission …

Biological, genetic and epigenetic markers in ulcerative colitis

G Caliendo, G D'Elia, J Makker, L Passariello… - Advances in Medical …, 2023 - Elsevier
In this review, we have summarized the existing knowledge of ulcerative colitis (UC) markers
based on current literature, specifically, the roles of potential new biomarkers, such as …

To STRIDE or not to STRIDE: a critique of “treat to target” in ulcerative colitis

KR Herrlinger, EF Stange - Expert Review of Gastroenterology & …, 2024 - Taylor & Francis
Introduction The STRIDE consensus intends to complement the clinical endpoint with an
endoscopic endpoint of mucosal healing and others as treatment targets in ulcerative colitis …