Human papillomavirus (HPV) is the most common sexually transmitted virus worldwide.
More than 99% of cervical cancer cases are associated with certain types of HPVs, termed …

Among the various immunological and non-immunological tumor-promoting activities of
myeloid-derived suppressor cells (MDSCs), their immunosuppressive capacity remains a …

Cytokines are critical for intercellular communication in human health and disease, but the
investigation of cytokine signaling activity has remained challenging due to the short half …

Background Deciphering intra‐and inter‐tumoural heterogeneity is essential for
understanding the biology of gastric cancer (GC) and its metastasis and identifying effective …

The expression “immunogenic cell death”(ICD) refers to a functionally unique form of cell
death that facilitates (instead of suppressing) a T cell-dependent immune response specific …

Induction of immunogenic cell death (ICD) plays crucial roles in cancer immunotherapy,
whereas its efficacy is severely compromised by redundant antioxidant defenses in cancer …

Dendritic-cells (DCs) have received considerable attention as potential targets for the
development of anticancer vaccines. DC-based anticancer vaccination relies on patient …

Bacterial sepsis and severe COVID-19 share similar clinical manifestations and are both
associated with dysregulation of the myeloid cell compartment. We previously reported an …

The introduction and the unexpected efficacy of checkpoint inhibitors (CPI) and more
recently of chimeric antigen receptor T cells (CAR T-cells) in the treatment of malignant …

Clinical and technological advances promoting early hemorrhage control and physiologic
resuscitation as well as early diagnosis and optimal treatment of sepsis have significantly …