The miR-29 family: genomics, cell biology, and relevance to renal and cardiovascular injury

AJ Kriegel, Y Liu, Y Fang, X Ding… - Physiological …, 2012 - journals.physiology.org
The human miR-29 family of microRNAs has three mature members, miR-29a, miR-29b, and
miR-29c. miR-29s are encoded by two gene clusters. Binding sites for several transcriptional …

Epigenetic regulation in AKI and kidney repair: mechanisms and therapeutic implications

C Guo, G Dong, X Liang, Z Dong - Nature Reviews Nephrology, 2019 - nature.com
Acute kidney injury (AKI) is a major public health concern associated with high morbidity and
mortality. Despite decades of research, the pathogenesis of AKI remains incompletely …

MicroRNA-29c in urinary exosome/microvesicle as a biomarker of renal fibrosis

LL Lv, YH Cao, HF Ni, M Xu, D Liu… - … of physiology-renal …, 2013 - journals.physiology.org
Micro (mi) RNAs are frequently dysregulated in the development of renal fibrosis. Exosomes
are small membrane vesicles that could be isolated from urine secreted from all nephron …

Anti-inflammatory role of microRNA-146a in the pathogenesis of diabetic nephropathy

K Bhatt, LL Lanting, Y Jia, S Yadav… - Journal of the …, 2016 - journals.lww.com
Inflammation has a critical role in the pathogenesis of diabetic complications, including
diabetic nephropathy (DN). MicroRNAs have recently emerged as important regulators of …

MicroRNAs expression profiles in cardiovascular diseases

E Bronze-da-Rocha - BioMed research international, 2014 - Wiley Online Library
The current search for new markers of cardiovascular diseases (CVDs) is explained by the
high morbidity and mortality still observed in developed and developing countries due to …

MicroRNAs in renal fibrosis

ACK Chung, HY Lan - Frontiers in physiology, 2015 - frontiersin.org
MicroRNAs (miRNAs) are endogenous short non-coding RNAs that regulate most of
important cellular processes by inhibiting gene expression through the post-transcriptional …

Identification of a microRNA signature in renal fibrosis: role of miR-21

A Zarjou, S Yang, E Abraham… - American Journal of …, 2011 - journals.physiology.org
Renal fibrosis is a final stage of many forms of kidney disease and leads to impairment of
kidney function. The molecular pathogenesis of renal fibrosis is currently not well …

microRNA crosstalk influences epithelial-to-mesenchymal, endothelial-to-mesenchymal, and macrophage-to-mesenchymal transitions in the kidney

SP Srivastava, AF Hedayat, K Kanasaki… - Frontiers in …, 2019 - frontiersin.org
microRNAs (miRNAs) are small, non-coding nucleotides that regulate diverse biological
processes. Altered microRNA biosynthesis or regulation contributes to pathological …

Urinary microRNA profiling in the nephropathy of type 1 diabetes

C Argyropoulos, K Wang, S McClarty, D Huang… - PloS one, 2013 - journals.plos.org
Background Patients with Type 1 Diabetes (T1D) are particularly vulnerable to development
of Diabetic nephropathy (DN) leading to End Stage Renal Disease. Hence a better …

[HTML][HTML] Non-coding RNAs in kidney injury and repair

Z Liu, Y Wang, S Shu, J Cai… - American Journal of …, 2019 - journals.physiology.org
Acute kidney injury (AKI) is a major kidney disease featured by a rapid decline of renal
function. Pathologically, AKI is characterized by tubular epithelial cell injury and death …