Background: Hypericin is a prominent secondary metabolite mainly existing in genus
Hypericum. It has become a research focus for a quiet long time owing to its extensively …

In this article, the scavenging ability of hypericin on hydroxyl radicals was evaluated by UV
spectra, HPLC and fluorescence spectra. The reaction mechanism of the scavenging of free …

Glioblastoma WHO IV belongs to a group of brain tumors that are still incurable. A promising
treatment approach applies photodynamic therapy (PDT) with hypericin as a …

The peripherical protons of the dye molecule hypericin can undergo structural
interconversion (tautomerization) between different isomers separated by a low energy …

The use of surface-enhanced Raman spectroscopy (SERS) in liquid solutions has always
been challenging due to signal fluctuations, inconsistent data, and difficulties in obtaining …

When confronted with a chemical physics problem, the standard approach has long been to
first simplify and limit the problem to a hypothetical molecule or a nanoscale unit in a …

Hypericin tautomerization that involves the migration of the labile protons is believed to be
the primary photophysical process relevant to its light-activated antiviral activity. Despite the …

Fluorescence lifetime imaging microscopy (FLIM) is an emerging tool to characterize
ongoing chemical reactions in synthetic chemistry and catalysis. Initially applied to biological …

The distortions and instability of high-symmetry configurations of polyatomic systems in
nondegenerate states are usually ascribed to the pseudo-Jahn-Teller effect (PJTE). The …

Hypericin has large potential in modern medicine and exhibits fascinating structural
dynamics, such as multiple conformations and tautomerization. However, it is difficult to …