Alpha‐linolenic acid: an omega‐3 fatty acid with neuroprotective properties—ready for use in the stroke clinic?

N Blondeau, RH Lipsky, M Bourourou… - BioMed research …, 2015 - Wiley Online Library
Alpha‐linolenic acid (ALA) is plant‐based essential omega‐3 polyunsaturated fatty acids
that must be obtained through the diet. This could explain in part why the severe deficiency …

Neural stem/progenitor cell transplantation for spinal cord injury treatment; A systematic review and meta-analysis

M Yousefifard, V Rahimi-Movaghar, F Nasirinezhad… - Neuroscience, 2016 - Elsevier
Despite the vast improvements of cell therapy in spinal cord injury treatment, no optimum
protocol has been developed for application of neural stem/progenitor cells. In this regard …

[HTML][HTML] Human Neural Stem Cells Differentiate and Promote Locomotor Recovery in an Early Chronic Spinal coRd Injury NOD-scid Mouse Model

DL Salazar, N Uchida, FPT Hamers, BJ Cummings… - PloS one, 2010 - journals.plos.org
Background Traumatic spinal cord injury (SCI) results in partial or complete paralysis and is
characterized by a loss of neurons and oligodendrocytes, axonal injury, and demyelination …

[HTML][HTML] Biomaterial-based Schwann cell transplantation and Schwann cell-derived biomaterials for nerve regeneration

Z Rao, Z Lin, P Song, D Quan, Y Bai - Frontiers in cellular …, 2022 - frontiersin.org
Schwann cells (SCs) dominate the regenerative behaviors after peripheral nerve injury by
supporting axonal regrowth and remyelination. Previous reports also demonstrated that the …

[HTML][HTML] Subchronic alpha-linolenic acid treatment enhances brain plasticity and exerts an antidepressant effect: a versatile potential therapy for stroke

N Blondeau, C Nguemeni, DN Debruyne… - …, 2009 - nature.com
Omega-3 polyunsaturated fatty acids are known to have therapeutic potential in several
neurological and psychiatric disorders. However, the molecular mechanisms of action …

Don't fence me in: harnessing the beneficial roles of astrocytes for spinal cord repair

RE White, LB Jakeman - Restorative neurology and …, 2008 - content.iospress.com
Astrocytes comprise a heterogeneous cell population that plays a complex role in repair
after spinal cord injury. Reactive astrocytes are major contributors to the glial scar that is a …

Engineering angiogenesis following spinal cord injury: a coculture of neural progenitor and endothelial cells in a degradable polymer implant leads to an increase in …

MF Rauch, SR Hynes, J Bertram… - European Journal of …, 2009 - Wiley Online Library
Angiogenesis precedes recovery following spinal cord injury and its extent correlates with
neural regeneration, suggesting that angiogenesis may play a role in repair. An important …

The transient receptor potential vanilloid‐2 cation channel impairs glioblastoma stem‐like cell proliferation and promotes differentiation

MB Morelli, M Nabissi, C Amantini… - … journal of cancer, 2012 - Wiley Online Library
Malignant transformation of cells resulting from enhanced proliferation and aberrant
differentiation is often accompanied by changes in transient receptor potential vanilloid …

[HTML][HTML] Neurosphere-derived cells exert a neuroprotective action by changing the ischemic microenvironment

C Capone, S Frigerio, S Fumagalli, M Gelati… - PloS one, 2007 - journals.plos.org
Background Neurosphere-derived cells (NC), containing neural stem cells, various
progenitors and more differentiated cells, were obtained from newborn C57/BL6 mice and …

[HTML][HTML] Feasibility of combination allogeneic stem cell therapy for spinal cord injury: a case report

TE Ichim, F Solano, F Lara, E Paris, F Ugalde… - International archives of …, 2010 - Springer
Cellular therapy for spinal cord injury (SCI) is overviewed focusing on bone marrow
mononuclear cells, olfactory ensheathing cells, and mesenchymal stem cells. A case is …