Heat shock protein 90 has roles in intracellular calcium homeostasis, protein tyrosine phosphorylation regulation, and progesterone-responsive sperm function in …
K Li, Y Xue, A Chen, Y Jiang, H Xie, Q Shi, S Zhang… - PloS one, 2014 - journals.plos.org
Heat shock protein 90 plays critical roles in client protein maturation, signal transduction,
protein folding and degradation, and morphological evolution; however, its function in …
protein folding and degradation, and morphological evolution; however, its function in …
What do secreted phospholipases A2 have to offer in combat against different viruses up to SARS-CoV-2?
Secreted phospholipases A 2 (sPLA 2 s) form a widespread group of structurally-related
enzymes that catalyse the hydrolysis of the sn-2 ester bond of glycerophospholipids to …
enzymes that catalyse the hydrolysis of the sn-2 ester bond of glycerophospholipids to …
Hsp90 interacts with Cdc37, is phosphorylated by PKA/PKC, and regulates Src phosphorylation in human sperm capacitation
K Li, P Sun, Y Wang, T Gao, D Zheng, A Liu, Y Ni - Andrology, 2021 - Wiley Online Library
Abstract Background Heat shock protein 90 (Hsp90) signaling pathways participate in
protein phosphorylation during sperm capacitation. However, the underlying mechanism is …
protein phosphorylation during sperm capacitation. However, the underlying mechanism is …
Proteomic analysis of sperm from fertile stallions and subfertile stallions due to impaired acrosomal exocytosis
C Hernández-Avilés, L Ramírez-Agámez… - Scientific reports, 2024 - nature.com
Thoroughbred stallions that carry a double-homozygous genotype A/AA/A for SNPs
rs397316122 and rs69101140 in exon 5 of the FKBP6 gene (chr13; EquCab3. 0) are …
rs397316122 and rs69101140 in exon 5 of the FKBP6 gene (chr13; EquCab3. 0) are …
Lipophilic phthalic acid esters impair human sperm acrosomal reaction through the likely inhibition of phospholipase A2-signaling pathway
I Cosci, A Garolla, A Cabrelle, S Sut… - Biochemical …, 2022 - Elsevier
Phthalic acid esters (PAEs) are recognized endocrine disruptors. Detection of PAEs in
semen from idiopathic infertile males suggests possible direct mechanisms of sperm toxicity …
semen from idiopathic infertile males suggests possible direct mechanisms of sperm toxicity …
The stallion sperm acrosome: Considerations from a research and clinical perspective
C Hernández-Avilés, L Ramírez-Agámez, DD Varner… - Theriogenology, 2023 - Elsevier
During the fertilization process, the interaction between the sperm and the oocyte is
mediated by a process known as acrosomal exocytosis (AE). Although the role of the sperm …
mediated by a process known as acrosomal exocytosis (AE). Although the role of the sperm …
Progesterone-induced acrosome exocytosis requires sequential involvement of calcium-independent phospholipase A2β (iPLA2β) and group X secreted …
R Abi Nahed, G Martinez, J Escoffier, S Yassine… - Journal of Biological …, 2016 - ASBMB
Phospholipase A 2 (PLA 2) activity has been shown to be involved in the sperm acrosome
reaction (AR), but the molecular identity of PLA 2 isoforms has remained elusive. Here, we …
reaction (AR), but the molecular identity of PLA 2 isoforms has remained elusive. Here, we …
Metabolites involved in cellular communication among human cumulus-oocyte-complex and sperm during in vitro fertilization
MJ Gómez-Torres, EM García, J Guerrero… - Reproductive Biology …, 2015 - Springer
Background Fertilization is a key physiological process for the preservation of the species.
Consequently, different mechanisms affecting the sperm and the oocyte have been …
Consequently, different mechanisms affecting the sperm and the oocyte have been …
Asthenozoospermia and membrane remodeling enzymes: a new role for phospholipase A2
CD Anfuso, M Olivieri, S Bellanca, M Salmeri… - …, 2015 - Wiley Online Library
Summary Phosholipase A2 (PLA 2) activity in the seminal plasma and in sperm heads is
closely related to sperm motility and male fertility. Therefore, the purpose of this study was to …
closely related to sperm motility and male fertility. Therefore, the purpose of this study was to …
[PDF][PDF] 分泌型磷脂酶A2 亚家族: 结构与功能
杨武， 郭薇， 黄春洪 - 2013 - academia.edu
摘要分泌型磷脂酶A2 (secretory phospholipase A2, sPLA2) 是磷脂代谢酶中最大的一个亚家族
, 具有多种生理功能. 迄今为止, 在人体中总共发现11 种sPLA2 亚型, 它们具有不同的组织分布 …
, 具有多种生理功能. 迄今为止, 在人体中总共发现11 种sPLA2 亚型, 它们具有不同的组织分布 …