Hypoxia has been shown to have a role in the pathogenesis of several forms of liver
disease. The hypoxia inducible factors (HIFs) are a family of evolutionarily conserved …

Liver fibrosis is a potentially reversible pathophysiological event, leading to excess
deposition of extracellular matrix (ECM) components and taking place as the net result of …

Genetic deficiency of Jak3 leads to abrogation of signal transduction through the common
gamma chain (γc) and thus to immunodeficiency suggesting that specific inhibition of Jak3 …

Oncostatin M (OSM) is a pleiotropic cytokine involved in a variety of inflammatory responses
such as wound healing, liver regeneration, and bone remodeling. As a member of the …

Mesenchymal stem cells (MSCs) have great potential for cell therapy in regenerative
medicine, including liver disease. Even though ongoing research is dedicated to the goal of …

Oncostatin M (OSM) is a pleiotropic cytokine of the interleukin (IL)‐6 family that contributes to
the progression of chronic liver disease. Here we investigated the role of OSM in the …

Simple Summary Pro-inflammatory cytokines play a key role in innate-and adaptive-
immunity-mediated liver carcinogenesis. Among these, oncostatin M (OSM) critically …

Background Systemic and chronic inflammatory conditions in patients with breast cancer
have been associated with reduced patient survival and increased breast cancer …

Background: Preclinical and epidemiologic studies suggest that garlic intake is inversely
associated with the progression of cancer and cardiovascular disease. Objective: We …

Abstract Background and objective Pulmonary Hypertension (pH) is a chronic progressive
disease. Endothelial cells (EC) play a central and critical role in the initiation and …