Conspectus The growing importance of axially chiral architectures in different scientific
domains has unveiled shortcomings in terms of efficient synthetic access and skeletal …

Atropisomerism is a stereochemical behavior portrayed by three-dimensional molecules that
bear rotationally restricted σ bond. Akin to the well-represented point-chiral molecules …

Conspectus Atropisomerism is a conformational chirality that occurs when there is hindered
rotation about a σ-bond. While atropisomerism is exemplified by biaryls, it is observed in …

Conspectus Axially chiral compounds have received much attention from chemists because
of their widespread appearance in natural products, biologically active compounds, and …

Axial chirality widely exists in natural products, pharmaceutical compounds, and other
functional molecules; these axially chiral compounds also find wide utility as catalysts or …

Conspectus Asymmetric functionalization of alkyl radicals represents a robust yet
underdeveloped method for efficient construction and decoration of carbon skeletons in …

Atropisomerism is a dynamic type of axial chirality that is ubiquitous in medicinal chemistry.
There are several examples of stable atropisomeric US FDA-approved drugs and …

The first catalytic asymmetric construction of 3, 3′‐bisindole skeletons bearing both axial
and central chirality has been established by organocatalytic asymmetric addition reactions …

Arylation is a fundamental reaction that can be mostly fulfilled by electrophilic aromatic
substitution and transition-metal-catalysed aryl functionalization. Although the azo group has …

The well‐defined conformational properties of axially chiral compounds bring extraordinary
values to an assortment of bioactive molecules, advanced materials, organocatalysts as well …