Respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD),
are critical areas of medical research, as millions of people are affected worldwide. In fact …

Representing severe morbidity and mortality globally, respiratory infections associated with
chronic respiratory diseases, including complicated pneumonia, asthma, interstitial lung …

The corneal epithelium is a layer in the anterior part of eye that contributes to light refraction
onto the retina and to the ocular immune defense. Although an intact corneal epithelium is …

Antimicrobial peptides (AMPs) are molecules with an amphipathic structure that enables
them to interact with bacterial membranes. This interaction can lead to membrane crossing …

Antimicrobial resistance is a silent pandemic harming human health, and Pseudomonas
aeruginosa is the most common bacterium responsible for chronic pulmonary and eye …

The number of antibiotic-resistant microbial infections is dramatically increasing, while the
discovery of new antibiotics is significantly declining. Furthermore, the activity of antibiotics is …

Antibiotic resistance has recently been recognized as an alarming issue and one of the
leading causes of death worldwide [1]. In the last few years, the frequent use of antibiotics in …

Respiratory infections are an extraordinary threat to human health and are among the top
ten causes of death globally, accounting for over half of all-cause mortality. According to the …

SET-M33 is a synthetic peptide that is being developed as a new antibiotic against major
Gram-negative bacteria. In this Ph. D. thesis the results about in vivo efficacy and toxicity in …